↓ Skip to main content

The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases

Overview of attention for article published in Archivum Immunologiae et Therapiae Experimentalis, June 2015
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#19 of 261)
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
70 Dimensions

Readers on

mendeley
157 Mendeley
Title
The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases
Published in
Archivum Immunologiae et Therapiae Experimentalis, June 2015
DOI 10.1007/s00005-015-0344-z
Pubmed ID
Authors

Jacek Tabarkiewicz, Katarzyna Pogoda, Agnieszka Karczmarczyk, Piotr Pozarowski, Krzysztof Giannopoulos

Abstract

The end of twentieth century has introduced some changes into T helper (Th) cells division. The identification of the new subpopulation of T helper cells producing IL-17 modified model of Th1-Th2 paradigm and it was named Th17. High abilities to stimulate acute and chronic inflammation made these cells ideal candidate for crucial player in development of autoimmune disorders. Numerous publications based on animal and human models confirmed their pivotal role in pathogenesis of human systemic and organ-specific autoimmune diseases. These findings made Th17 cells and pathways regulating their development and function a good target for therapy. Therapies based on inhibition of Th17-dependent pathways are associated with clinical benefits, but on the other hand are frequently inducing adverse effects. In this review, we attempt to summarize researches focused on the importance of Th17 cells in development of human autoimmune diseases as well as effectiveness of targeting IL-17 and its pathways in pre-clinical and clinical studies.

Mendeley readers

The data shown below were compiled from readership statistics for 157 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Brazil 1 <1%
Poland 1 <1%
Canada 1 <1%
Unknown 152 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 23%
Student > Bachelor 28 18%
Student > Master 27 17%
Unspecified 18 11%
Student > Doctoral Student 17 11%
Other 31 20%
Readers by discipline Count As %
Medicine and Dentistry 35 22%
Biochemistry, Genetics and Molecular Biology 28 18%
Unspecified 26 17%
Agricultural and Biological Sciences 26 17%
Immunology and Microbiology 24 15%
Other 18 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2016.
All research outputs
#1,951,662
of 12,545,170 outputs
Outputs from Archivum Immunologiae et Therapiae Experimentalis
#19
of 261 outputs
Outputs of similar age
#53,570
of 261,255 outputs
Outputs of similar age from Archivum Immunologiae et Therapiae Experimentalis
#1
of 10 outputs
Altmetric has tracked 12,545,170 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 261 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,255 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them