Title |
Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR
|
---|---|
Published in |
Graefe's Archive for Clinical and Experimental Ophthalmology, August 2012
|
DOI | 10.1007/s00417-012-2130-5 |
Pubmed ID | |
Authors |
Marco Adán Juárez–Verdayes, Sandra Rodríguez–Martínez, Mario E. Cancino–Diaz, Juan C. Cancino–Diaz |
Abstract |
Keratitis caused by Staphylococcus aureus often leads to Vascular Endothelial Growth Factor (VEGF)-dependent neovascularization, but contribution of peptidoglycan (PGN), muramyl dipeptide (MDP) and lipoteichoic acid (LTA) from S. aureus to VEGF-dependent neovascularization has not been well-studied. This work was focused on the analysis of S. aureus cell wall components in the production of VEGF family members (VEGF-A, VEGF-B, VEGF-C and VEGF-D) in ocular limbal fibroblasts. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 5% |
United States | 1 | 5% |
Unknown | 20 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 23% |
Other | 4 | 18% |
Researcher | 3 | 14% |
Student > Doctoral Student | 2 | 9% |
Professor > Associate Professor | 2 | 9% |
Other | 3 | 14% |
Unknown | 3 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 23% |
Agricultural and Biological Sciences | 4 | 18% |
Immunology and Microbiology | 4 | 18% |
Biochemistry, Genetics and Molecular Biology | 3 | 14% |
Nursing and Health Professions | 1 | 5% |
Other | 0 | 0% |
Unknown | 5 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2012.
All research outputs
#20,435,228
of 25,986,827 outputs
Outputs from Graefe's Archive for Clinical and Experimental Ophthalmology
#1
of 2 outputs
Outputs of similar age
#143,028
of 187,241 outputs
Outputs of similar age from Graefe's Archive for Clinical and Experimental Ophthalmology
#9
of 15 outputs
Altmetric has tracked 25,986,827 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2 research outputs from this source. They receive a mean Attention Score of 0.6. This one scored the same or higher as 1 of them.
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.