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Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR

Overview of attention for article published in Graefe's Archive for Clinical and Experimental Ophthalmology, August 2012
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Title
Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology, August 2012
DOI 10.1007/s00417-012-2130-5
Pubmed ID
Authors

Marco Adán Juárez–Verdayes, Sandra Rodríguez–Martínez, Mario E. Cancino–Diaz, Juan C. Cancino–Diaz

Abstract

Keratitis caused by Staphylococcus aureus often leads to Vascular Endothelial Growth Factor (VEGF)-dependent neovascularization, but contribution of peptidoglycan (PGN), muramyl dipeptide (MDP) and lipoteichoic acid (LTA) from S. aureus to VEGF-dependent neovascularization has not been well-studied. This work was focused on the analysis of S. aureus cell wall components in the production of VEGF family members (VEGF-A, VEGF-B, VEGF-C and VEGF-D) in ocular limbal fibroblasts.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
United States 1 5%
Unknown 20 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 23%
Other 4 18%
Researcher 3 14%
Student > Doctoral Student 2 9%
Professor > Associate Professor 2 9%
Other 3 14%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 5 23%
Agricultural and Biological Sciences 4 18%
Immunology and Microbiology 4 18%
Biochemistry, Genetics and Molecular Biology 3 14%
Nursing and Health Professions 1 5%
Other 0 0%
Unknown 5 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2012.
All research outputs
#20,435,228
of 25,986,827 outputs
Outputs from Graefe's Archive for Clinical and Experimental Ophthalmology
#1
of 2 outputs
Outputs of similar age
#143,028
of 187,241 outputs
Outputs of similar age from Graefe's Archive for Clinical and Experimental Ophthalmology
#9
of 15 outputs
Altmetric has tracked 25,986,827 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2 research outputs from this source. They receive a mean Attention Score of 0.6. This one scored the same or higher as 1 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,241 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.