| Title |
Mechanism of human rhinovirus infections
|
|---|---|
| Published in |
Molecular and Cellular Pediatrics, June 2016
|
| DOI | 10.1186/s40348-016-0049-3 |
| Pubmed ID | |
| Authors |
Dieter Blaas, Renate Fuchs |
| Abstract |
About 150 human rhinovirus serotypes are responsible for more than 50 % of recurrent upper respiratory infections. Despite having similar 3D structures, some bind members of the low-density lipoprotein receptor family, some ICAM-1, and some use CDHR3 for host cell infection. This is also reflected in the pathways exploited for cellular entry. We found that even rhinovirus serotypes binding the same receptor can travel along different endocytic pathways and release their RNA genome into the cytosol at different locations. How this may account for distinct immune responses elicited by various rhinoviruses and the observed symptoms of the common cold is briefly discussed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 196 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 196 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 44 | 22% |
| Student > Ph. D. Student | 25 | 13% |
| Student > Master | 22 | 11% |
| Researcher | 15 | 8% |
| Student > Doctoral Student | 10 | 5% |
| Other | 30 | 15% |
| Unknown | 50 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 50 | 26% |
| Immunology and Microbiology | 23 | 12% |
| Agricultural and Biological Sciences | 21 | 11% |
| Medicine and Dentistry | 21 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 4% |
| Other | 19 | 10% |
| Unknown | 54 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 216. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2021.
All research outputs
#174,928
of 25,068,002 outputs
Outputs from Molecular and Cellular Pediatrics
#2
of 112 outputs
Outputs of similar age
#3,386
of 346,404 outputs
Outputs of similar age from Molecular and Cellular Pediatrics
#2
of 6 outputs
Altmetric has tracked 25,068,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 112 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.