| Title |
Synthesis and evaluation of antitumor activities of novel chiral 1,2,4-triazole Schiff bases bearing γ-butenolide moiety
|
|---|---|
| Published in |
BMC Chemistry, July 2012
|
| DOI | 10.1186/2191-2858-2-26 |
| Pubmed ID | |
| Authors |
Xiang Li, Xue-Qiang Li, He-Mei Liu, Xue-Zhang Zhou, Zhi-Hui Shao |
| Abstract |
1,2,4-Triazole derivatives have received much attention due to their versatile biological properties including antibacterial, antifungal, anticonvulsant, antiinflammatory, anticancer, and antiproliferative properties. 1,2,4-Triazole nucleus has been incorporated into a wide variety of therapeutically interesting molecules to transform them into better drugs. Schiff bases of 1,2,4-triazoles have also been found to possess extensive biological activities. On the other hand, γ-substituted butenolide moiety represents a biological important entity that is present in numerous biologically active natural products. |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 24% |
| Student > Master | 10 | 18% |
| Researcher | 4 | 7% |
| Student > Bachelor | 3 | 5% |
| Student > Doctoral Student | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 18 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 23 | 42% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
| Medicine and Dentistry | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 18 | 33% |