| Title |
Influence of pH and carbon to nitrogen ratio on mycotoxin production by Alternaria alternata in submerged cultivation
|
|---|---|
| Published in |
AMB Express, May 2012
|
| DOI | 10.1186/2191-0855-2-28 |
| Pubmed ID | |
| Authors |
Katrin Brzonkalik, Dominik Hümmer, Christoph Syldatk, Anke Neumann |
| Abstract |
Production of the Alternaria mycotoxins alternariol (AOH), alternariol monomethylether (AME) and tenuazonic acid (TA) by Alternaria alternata DSM 12633 was influenced by pH and carbon to nitrogen (C:N) ratio of the growth medium both in shaking flasks and bioreactor cultivation. The impact of medium pH on mycotoxin production was studied in the range of pH 3.5 - 8. pH values above 5.5 led to a decreased mycotoxin production or inhibited mycotoxin formation completely whereas an acidic pH in the range of 4.0-4.5 was optimal for mycotoxin production. The influence of the C:N ratio was evaluated over the range of 24 to 96. Glucose was used as carbon source and its concentration was altered while nitrogen concentration was kept constant. Growth kinetics and mycotoxin production parameters were studied depending on different C:N ratios. With increasing initial glucose concentration fungal biomass did increase but the maximum specific growth rate was not influenced. The optimal initial C:N ratio for attaining highest mycotoxin concentrations was 72. A higher C:N ratio did not further enhance mycotoxin production. |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Poland | 1 | 2% |
| Czechia | 1 | 2% |
| France | 1 | 2% |
| Unknown | 50 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 23% |
| Student > Master | 9 | 17% |
| Student > Bachelor | 7 | 13% |
| Researcher | 7 | 13% |
| Lecturer | 2 | 4% |
| Other | 7 | 13% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 45% |
| Biochemistry, Genetics and Molecular Biology | 6 | 11% |
| Chemistry | 4 | 8% |
| Chemical Engineering | 2 | 4% |
| Unspecified | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 11 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2012.
All research outputs
#20,157,329
of 22,665,794 outputs
Outputs from AMB Express
#963
of 1,227 outputs
Outputs of similar age
#147,861
of 163,617 outputs
Outputs of similar age from AMB Express
#3
of 5 outputs
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So far Altmetric has tracked 1,227 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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