@lchfRD Started low carb June 2016 so basically passed after 2.5 years. The 2019 test was done by a lab & measured insulin. 2020 was a self-test only with glucose. Both are plotted against data from this useful paper. https://t.co/vK0CVDXacR
@mario_kratz @DikemanDave @Dr__Guess or cgm... (& better if ogtt done with an insulin assay) you really don't have a good picture. Folks should know where they are on this spectrum. https://t.co/KcS9GcA79i https://t.co/kpXWRC6Hw6
@FrogHarmless @DIY_Tardis @tednaiman This is my "go-to" paper to understand where one sits on the T2DM spectrum. See figure 1. Not found anything better. https://t.co/2iZkGE1ZJn
@CaloriesProper @ZKForTre @runsalot48 You can see how that plays out in this population which while not longitudinal displays the progression. See figure 1. https://t.co/KcS9GcRabi
@Nutradvance In this study, 2% of a middle aged & aged Finnish cohort had T2DM. 13% were normal. 85% were abnormal & somewhere on the T2DM spectrum. Why should they wait until a T2DM Dx to know to act? US even worse! https://t.co/KcS9GcRabi
RT @MacroFour: @realDaveFeldman @Plant_proof Study: 85% had an abnormal response on the 'diabetes spectrum' while only 13% were normal & 2%…
@realDaveFeldman @Plant_proof Study: 85% had an abnormal response on the 'diabetes spectrum' while only 13% were normal & 2% had diabetes. 85% are on their way to diabetes thinking they are healthy & might act to prevent it by restricting carbs if
@REGISMOREAU @bcorkey If you have T2 diabetes, there is no way that you have a normal glucose response. This paper showed in 5340 middle-aged & senior Finns, only 13% were normal & most would never know it. https://t.co/KcS9GcA79i
@ZKForTre @thom_bennett The base diagram from my plots is the most useful I have seen. They weren't young but included insulin sensitive with NGT. The kinds of curves you seek would probably be in their data. https://t.co/KcS9GcRabi
@MyNutritionSci @ScepticalDoctor @FusionProgGuy @BioLayne Except you don't just need to be pre-diabetic or diabetic to have physiologically abnormal BG. See Table 1. 1898/4745 = 40% of this cohort (46-year-olds) were abnormal. https://t.co/KcS9GcRabi
@lchfRD @maximumcharacte Why? Poor 1st phase insulin response means early BG is high & may be a genetic defect leading to T2DM remaining even after insulin sensitivity is restored & 2 hr OGTT can be passed. This appears to be my case. Refs: https:
@EricTopol @CDCgov @CDCMMWR “Insulin-resistant non-diabetic individuals are exposed to a similar adverse postprandial metabolic milieu, and analogous cardiometabolic risk, as those with type 2 diabetes.” https://t.co/4OSFqmiaIk
@ScepticalDoctor @Thrival1 @JimJohnsonSci @DrPaulMason The subjects were all about 30 & slightly overweight so all were probably quite insulin sensitive & had normal glucose tolerance. I don't see what other conclusion you could draw from Wang et a
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
RT @jejkarppinen: Changes in blood metabolome during an OGTT associate with metabolic health status. A very interesting new study! https://…
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
@QinFinn @johanneskettune @MakinenGroup
RT @jejkarppinen: Changes in blood metabolome during an OGTT associate with metabolic health status. A very interesting new study! https://…
Insulin Resistance and Systemic Metabolic Changes in Oral Glucose Tolerance Test in 5340 Individuals: An Interventional Study https://t.co/EHrY8ymfeM
RT @jejkarppinen: Changes in blood metabolome during an OGTT associate with metabolic health status. A very interesting new study! https://…
Changes in blood metabolome during an OGTT associate with metabolic health status. A very interesting new study!
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
RT @mak_sysepi: Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discover…
Beautiful separation of metabolic behaviours btw clinically relevant groups of people in OGTT in 5340 individuals (discoveries in 4745 and a replication in 595 Finns); 4 time points, 78 metabolic measures; 5 groups ref IR and glucose @BMCMedicine https://t
RT @BMCMedicine: NEW #Research form Qin Wang and colleagues: #Insulin resistance and systemic metabolic changes in oral #glucose tolerance…
Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study (open access) https://t.co/VRlx0GkNwE #MetabolicSyndrome #InsulinResistance #BloodSugar #Triglycerides
Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study. https://t.co/0HWUoXSRAP
Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study. https://t.co/nJV9wkWFZt
NEW #Research form Qin Wang and colleagues: #Insulin resistance and systemic metabolic changes in oral #glucose tolerance test in 5340 individuals: an interventional study Read more here: https://t.co/RjYchO6f4R https://t.co/p4LuxnFkUN