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Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Overview of attention for article published in BMC Biology, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
5 tweeters
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
377 Dimensions

Readers on

mendeley
717 Mendeley
Title
Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
Published in
BMC Biology, January 2012
DOI 10.1186/1741-7007-10-29
Pubmed ID
Authors

Maria Vinci, Sharon Gowan, Frances Boxall, Lisa Patterson, Miriam Zimmermann, William Court, Cara Lomas, Marta Mendiola, David Hardisson, Suzanne A Eccles

Abstract

There is overwhelming evidence that in vitro three-dimensional tumor cell cultures more accurately reflect the complex in vivo microenvironment than simple two-dimensional cell monolayers, not least with respect to gene expression profiles, signaling pathway activity and drug sensitivity. However, most currently available three-dimensional techniques are time consuming and/or lack reproducibility; thus standardized and rapid protocols are urgently needed.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 717 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 1%
United Kingdom 5 <1%
France 4 <1%
Germany 3 <1%
Switzerland 3 <1%
Denmark 2 <1%
Malaysia 2 <1%
Italy 2 <1%
Spain 2 <1%
Other 8 1%
Unknown 677 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 201 28%
Researcher 154 21%
Student > Master 105 15%
Student > Bachelor 75 10%
Student > Doctoral Student 42 6%
Other 140 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 279 39%
Biochemistry, Genetics and Molecular Biology 137 19%
Medicine and Dentistry 71 10%
Unspecified 68 9%
Engineering 46 6%
Other 116 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2017.
All research outputs
#2,805,901
of 12,554,200 outputs
Outputs from BMC Biology
#637
of 1,132 outputs
Outputs of similar age
#23,755
of 118,068 outputs
Outputs of similar age from BMC Biology
#3
of 6 outputs
Altmetric has tracked 12,554,200 research outputs across all sources so far. Compared to these this one has done well and is in the 77th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 118,068 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.