Title |
Bone and Celiac Disease
|
---|---|
Published in |
Current Osteoporosis Reports, February 2016
|
DOI | 10.1007/s11914-016-0304-5 |
Pubmed ID | |
Authors |
María Belén Zanchetta, Vanesa Longobardi, Julio César Bai |
Abstract |
More than 50 % of untreated patients with celiac disease (CD) have bone loss detected by bone densitometry (dual-energy X-ray absorptiometry:DXA). Moreover, patients with CD are more likely to have osteoporosis and fragility fractures, especially of the distal radius. Although still controversial, we recommend DXA screening in all celiac disease patients, particularly in those with symptomatic CD at diagnosis and in those who present risk factors for fracture such as older age, menopausal status, previous fracture history, and familial hip fracture history. Bone microarchitecture, especially the trabecular network, may be deteriorated, explaining the higher fracture risk in these patients. Adequate calcium and vitamin D supplementation are also recommended to optimize bone recovery, especially during the first years of gluten free diet (GFD). If higher fracture risk persists after 1 or 2 years of GFD, specific osteoactive treatment may be necessary to improve bone health. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 29% |
United States | 2 | 29% |
Spain | 1 | 14% |
Netherlands | 1 | 14% |
Chile | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 57% |
Scientists | 2 | 29% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 122 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 15% |
Researcher | 15 | 12% |
Student > Doctoral Student | 12 | 10% |
Student > Master | 10 | 8% |
Student > Ph. D. Student | 7 | 6% |
Other | 23 | 19% |
Unknown | 37 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 33% |
Agricultural and Biological Sciences | 11 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 6% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Nursing and Health Professions | 3 | 2% |
Other | 13 | 11% |
Unknown | 43 | 35% |