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The endothelial glycocalyx: composition, functions, and visualization

Overview of attention for article published in Pflugers Archiv European Journal of Physiology, January 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#30 of 1,253)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

blogs
2 blogs
policy
1 policy source
twitter
2 tweeters

Citations

dimensions_citation
731 Dimensions

Readers on

mendeley
735 Mendeley
citeulike
1 CiteULike
Title
The endothelial glycocalyx: composition, functions, and visualization
Published in
Pflugers Archiv European Journal of Physiology, January 2007
DOI 10.1007/s00424-007-0212-8
Pubmed ID
Authors

Sietze Reitsma, Dick W. Slaaf, Hans Vink, Marc A. M. J. van Zandvoort, Mirjam G. A. oude Egbrink

Abstract

This review aims at presenting state-of-the-art knowledge on the composition and functions of the endothelial glycocalyx. The endothelial glycocalyx is a network of membrane-bound proteoglycans and glycoproteins, covering the endothelium luminally. Both endothelium- and plasma-derived soluble molecules integrate into this mesh. Over the past decade, insight has been gained into the role of the glycocalyx in vascular physiology and pathology, including mechanotransduction, hemostasis, signaling, and blood cell-vessel wall interactions. The contribution of the glycocalyx to diabetes, ischemia/reperfusion, and atherosclerosis is also reviewed. Experimental data from the micro- and macrocirculation alludes at a vasculoprotective role for the glycocalyx. Assessing this possible role of the endothelial glycocalyx requires reliable visualization of this delicate layer, which is a great challenge. An overview is given of the various ways in which the endothelial glycocalyx has been visualized up to now, including first data from two-photon microscopic imaging.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 735 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 11 1%
United Kingdom 5 <1%
Switzerland 5 <1%
Germany 4 <1%
Netherlands 4 <1%
Russia 3 <1%
Korea, Republic of 2 <1%
Hungary 2 <1%
Canada 2 <1%
Other 10 1%
Unknown 687 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 213 29%
Researcher 118 16%
Student > Master 96 13%
Student > Bachelor 80 11%
Student > Doctoral Student 49 7%
Other 179 24%
Readers by discipline Count As %
Medicine and Dentistry 209 28%
Agricultural and Biological Sciences 169 23%
Biochemistry, Genetics and Molecular Biology 73 10%
Engineering 64 9%
Unspecified 64 9%
Other 156 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2019.
All research outputs
#953,225
of 13,610,796 outputs
Outputs from Pflugers Archiv European Journal of Physiology
#30
of 1,253 outputs
Outputs of similar age
#11,993
of 209,850 outputs
Outputs of similar age from Pflugers Archiv European Journal of Physiology
#5
of 13 outputs
Altmetric has tracked 13,610,796 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,253 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,850 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.