The diagnostic accuracy of dopamine transporter SPECT imaging to detect nigrostriatal cell loss in patients with Parkinson’s disease or clinically uncertain parkinsonism: a systematic review

@captshoehorn Specificity is to pre-synaptic Parkinsonism generally, but sensitivity to specific forms varies. Really high in PDD, and by extension PDD (https://t.co/LWrOkRaEQt) but sens less in DLB, 70ish or a bit higher sensitivity since can be cortical

@djnicholl @doctorcaldwell @Laconic_doc @RogueRad OK thanks David. This 2015 syst rev by @svensuwijn et al indicates that DAT SPECT imaging seems to be accurate to detect nigrostriatal cell loss in patients with parkinsonism https://t.co/4pbfSCMGVX