| Title |
The use of a novel cleaning closed suction system reduces the volume of secretions within the endotracheal tube as assessed by micro-computed tomography: a randomized clinical trial
|
|---|---|
| Published in |
Annals of Intensive Care, December 2015
|
| DOI | 10.1186/s13613-015-0101-9 |
| Pubmed ID | |
| Authors |
Andrea Coppadoro, Giacomo Bellani, Alfio Bronco, Alberto Lucchini, Simone Bramati, Vanessa Zambelli, Roberto Marcolin, Antonio Pesenti |
| Abstract |
Early after intubation, a layer of biofilm covers the inner lumen of the endotracheal tube (ETT). Cleaning the ETT might prevent airways colonization by pathogens, reduce resistance to airflow, and decrease sudden ETT obstruction. We investigated the effectiveness of a cleaning closed suction system in maintaining the endotracheal tube free from secretions. We conducted a single center, randomized controlled trial, in the general intensive care unit of a tertiary-level university hospital. We enrolled 40 adult critically ill patients expected to remain intubated for more than 48 h, within 24 h from intubation. Patients were randomized to receive three ETT cleaning maneuvers/day using a novel device (Airway Medix Closed Suction System™, cleaning group) or to standard care (no ETT cleaning, standard closed suction, control group). After extubation, the amount of secretions in the ETTs was measured by micro-computed tomography. The volume of secretions in the ETTs from the cleaning group was lower than controls (0.081 [0.021-0.306] vs. 0.568 [0.162-0.756] mL, p = 0.001), corresponding to a cross-sectional area reduction six times lower (1[0-3] vs. 6 [2-10] %, p = 0.001). In a subset of 16 patients, the resistance to airflow tended to be lower after 1 day of treatment (p = 0.063) and was lower after 2 days (0.024), while no difference was present at enrollment (p = 0.922). ETT colonization did not differ between the two groups. The use of a novel cleaning closed suction system proved to be effective in reducing secretions present in the ETT after extubation, possibly reducing resistance to airflow during intubation. clinicaltrials.gov NCT01912105. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 20% |
| Argentina | 2 | 20% |
| Italy | 1 | 10% |
| United Kingdom | 1 | 10% |
| Australia | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 70% |
| Science communicators (journalists, bloggers, editors) | 2 | 20% |
| Scientists | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 15% |
| Other | 4 | 12% |
| Student > Master | 3 | 9% |
| Student > Doctoral Student | 3 | 9% |
| Researcher | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 15 | 44% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 7 | 21% |
| Medicine and Dentistry | 5 | 15% |
| Agricultural and Biological Sciences | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Arts and Humanities | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 18 | 53% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2016.
All research outputs
#5,154,497
of 24,896,578 outputs
Outputs from Annals of Intensive Care
#578
of 1,152 outputs
Outputs of similar age
#83,104
of 405,173 outputs
Outputs of similar age from Annals of Intensive Care
#9
of 30 outputs
Altmetric has tracked 24,896,578 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,152 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.4. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 405,173 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.