| Title |
Rituximab and bilateral HSV epithelial keratitis in a patient with mucous membrane pemphigoid
|
|---|---|
| Published in |
Journal of Ophthalmic Inflammation and Infection, August 2018
|
| DOI | 10.1186/s12348-018-0153-8 |
| Pubmed ID | |
| Authors |
W. Bernauer, S. Schuler, L. Borradori |
| Abstract |
B cell depleting therapy is widely used for lymphoproliferative diseases and immune-mediated disorders, including mucous membrane pemphigoid. The latter is an autoimmune blistering disease affecting predominantly the mucosae potentially associated with devastating complications. A 71-year-old patient with severe mucous membrane pemphigoid involving ocular, oral pharyngeal and laryngeal involvement is described. To control the disease, the patient was given rituximab therapy in combination with oral corticosteroids. He subsequently experienced an epithelial herpes simplex virus keratitis in one eye and 3 months later in his fellow eye. Topical treatment with ganciclovir resulted in prompt recovery. For the first time, a correlation between rituximab and bilateral epithelial herpes simplex virus keratitis is described. Although rituximab is a promising biologic agent for the treatment of autoimmune diseases, it bears the risk of reactivation of viral infections, including the onset of herpes simplex virus keratitis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 23% |
| Student > Doctoral Student | 2 | 15% |
| Student > Bachelor | 1 | 8% |
| Other | 1 | 8% |
| Student > Ph. D. Student | 1 | 8% |
| Other | 3 | 23% |
| Unknown | 2 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 69% |
| Immunology and Microbiology | 1 | 8% |
| Unknown | 3 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2018.
All research outputs
#20,663,600
of 25,385,509 outputs
Outputs from Journal of Ophthalmic Inflammation and Infection
#141
of 216 outputs
Outputs of similar age
#266,386
of 342,525 outputs
Outputs of similar age from Journal of Ophthalmic Inflammation and Infection
#1
of 1 outputs
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