Title |
Some patients (and some of us) respond better to some biological therapies: the as yet unsolved conundrum
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Published in |
Journal of Orthopaedics and Traumatology, August 2018
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DOI | 10.1186/s10195-018-0505-z |
Pubmed ID | |
Authors |
Isabel Andia, Nicola Maffulli |
Abstract |
Very often, treatment for many common musculoskeletal conditions is only palliative, or involves surgery with major shortcomings. Biological interventions-in particular, platelet-rich plasma (PRP) therapies-may well provide more effective treatments, but their actual efficacy is under scrutiny. PRP is biologically unique to each individual depending on endogenous and exogenous factors, including, but not limited to, demographic factors (i.e. age), immune status (i.e. microbiota), metabolic diseases and concomitant medications. All these potential modifiers of the ultimate effects of PRP have been poorly explored, and their relationship with efficacy has not been established. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 4 | 29% |
Other | 2 | 14% |
Student > Postgraduate | 2 | 14% |
Student > Doctoral Student | 1 | 7% |
Unknown | 5 | 36% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 29% |
Agricultural and Biological Sciences | 2 | 14% |
Neuroscience | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Unknown | 6 | 43% |