| Title |
A Systematic Review of the Acute Effects of Exercise on Immune and Inflammatory Indices in Untrained Adults
|
|---|---|
| Published in |
Sports Medicine - Open, October 2015
|
| DOI | 10.1186/s40798-015-0032-x |
| Pubmed ID | |
| Authors |
William M. C. Brown, Gareth W. Davison, Conor M. McClean, Marie H. Murphy |
| Abstract |
Cardiovascular disease (CVD) is the leading cause of global mortality. Although the incidence may be reduced with regular exercise, the health benefits of a single bout of exercise on selected CVD risk factors are not well understood. The primary objective of this review is to consider the transient effects of exercise on immune (neutrophil count) and inflammatory (interleukin-6 [IL-6], C-reactive protein [CRP]) markers in untrained adults. MEDLINE, EMBASE, CINAHL, Sports Discus and Cochrane were searched for relevant studies published from January 1946 to May 2013. Randomised controlled or crossover studies which measured any of these parameters in untrained but otherwise healthy participants in the 48 h following about of exercise, less than 1 h in duration were included. Ten studies met the inclusion criteria. The results indicate a single bout of aerobic or resistance exercise of moderate to high intensity promotes an increase in IL-6 (145 %) and neutrophil counts (51 %). It appears that 30-60 min of moderate to high intensity exercise is necessary to elicit such changes although variables such as the mode, intensity and pattern of exercise also affect the response. The acute response of CRP within the included studies is equivocal. Although responses to CRP are inconsistent, a single bout of exercise can increase the activity of both circulating IL-6 and neutrophil counts in untrained adults. These immune and inflammatory responses to a single bout of exercise may be linked to a range of health benefits. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 9 | 39% |
| United States | 3 | 13% |
| Australia | 2 | 9% |
| Norway | 1 | 4% |
| Greece | 1 | 4% |
| Guatemala | 1 | 4% |
| Unknown | 6 | 26% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 10 | 43% |
| Members of the public | 9 | 39% |
| Practitioners (doctors, other healthcare professionals) | 4 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 225 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Greece | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 220 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 48 | 21% |
| Student > Ph. D. Student | 34 | 15% |
| Student > Bachelor | 31 | 14% |
| Researcher | 16 | 7% |
| Student > Doctoral Student | 11 | 5% |
| Other | 43 | 19% |
| Unknown | 42 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 16% |
| Sports and Recreations | 35 | 16% |
| Nursing and Health Professions | 35 | 16% |
| Agricultural and Biological Sciences | 18 | 8% |
| Biochemistry, Genetics and Molecular Biology | 13 | 6% |
| Other | 37 | 16% |
| Unknown | 51 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2022.
All research outputs
#982,933
of 23,230,825 outputs
Outputs from Sports Medicine - Open
#86
of 487 outputs
Outputs of similar age
#15,890
of 284,021 outputs
Outputs of similar age from Sports Medicine - Open
#2
of 9 outputs
Altmetric has tracked 23,230,825 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 487 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.9. This one has done well, scoring higher than 82% of its peers.
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We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.