Title |
Looking on the “brite” side exercise-induced browning of white adipose tissue
|
---|---|
Published in |
Pflügers Archiv - European Journal of Physiology, July 2018
|
DOI | 10.1007/s00424-018-2177-1 |
Pubmed ID | |
Authors |
Logan K. Townsend, David C. Wright |
Abstract |
The need for effective and convenient ways of combatting obesity has created great interest in brown adipose tissue (BAT). However, because adult humans have relatively little amounts of BAT, the possibility of browning white adipose tissue (WAT), i.e., switching the metabolism of WAT from an energy storing to energy burning organ, has gained considerable attention. Exercise has countless health benefits, and has consistently been shown to cause browning in rodent white adipose tissue. The purpose of this review is to provide an overview of recent studies examining the effects of exercise and other interventions on the browning of white adipose tissue. The role of various endocrine factors, including catecholamines, interleukin-6, irisin, and meteorin-like in addition to local re-esterification-mediated mechanisms in inducing the browning of WAT will be discussed. The physiological importance of browning will be discussed, as will discrepancies in the literature between human and rodent studies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 66 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 14% |
Student > Doctoral Student | 9 | 14% |
Student > Master | 7 | 11% |
Student > Bachelor | 4 | 6% |
Researcher | 4 | 6% |
Other | 7 | 11% |
Unknown | 26 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 11 | 17% |
Medicine and Dentistry | 11 | 17% |
Sports and Recreations | 5 | 8% |
Agricultural and Biological Sciences | 2 | 3% |
Computer Science | 2 | 3% |
Other | 6 | 9% |
Unknown | 29 | 44% |