| Title |
Evaluation of clinical trial of atopic dermatitis by a topical cream containing the extracts from photosynthetic bacteria, Rhodobacter sphaeroides
|
|---|---|
| Published in |
AMB Express, August 2015
|
| DOI | 10.1186/s13568-015-0133-4 |
| Pubmed ID | |
| Authors |
Nam Young Kim, Jeong Sub Cho, Hyeon Yong Lee |
| Abstract |
The photosynthetic bacteria Rhodobacter sphaeroides has been studied as a functional food source; however, in this clinical study, we report for the first time its use as a treatment for atopic dermatitis. Topical cream containing 10% (v/v) extract was demonstrated to have the ability to reduce skin moisture content loss and pruritus by 27.82% in clinical trials for atopic dermatitis compared with controls. In particular, there were statistically significant differences in the pH and temperature changes of the skin, skin firmness and general skin appearance. Changes in the skin pH were measured as 4.83, and there was a 3.37% change in temperature after 4 weeks of treatment. It was also found that there were great differences in wrinkle states according to the grading scale of patients before and after treatment with topical cream. Therefore, these results strongly suggest that extracts from photosynthetic bacteria can be employed to soothe atopic irritation as a new cosmetic bioresource. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 33% |
| Student > Postgraduate | 2 | 22% |
| Student > Doctoral Student | 1 | 11% |
| Student > Ph. D. Student | 1 | 11% |
| Student > Bachelor | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 1 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 22% |
| Medicine and Dentistry | 2 | 22% |
| Nursing and Health Professions | 1 | 11% |
| Biochemistry, Genetics and Molecular Biology | 1 | 11% |
| Chemistry | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 2 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#15,342,608
of 22,821,814 outputs
Outputs from AMB Express
#445
of 1,234 outputs
Outputs of similar age
#155,012
of 264,494 outputs
Outputs of similar age from AMB Express
#17
of 26 outputs
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