| Title |
Bacteriological profile and antimicrobial susceptibility patterns of blood culture isolates among febrile patients in Mekelle Hospital, Northern Ethiopia
|
|---|---|
| Published in |
SpringerPlus, July 2015
|
| DOI | 10.1186/s40064-015-1056-x |
| Pubmed ID | |
| Authors |
Araya Gebreyesus Wasihun, Letemichael Negash Wlekidan, Senay Aregawi Gebremariam, Tsehaye Asmelash Dejene, Abadi Luel Welderufael, Tadesse Dejenie Haile, Saravanan Muthupandian |
| Abstract |
Bacterial bloodstream infections are a major public health problem, which leads to high morbidity and mortality of patients. On time diagnosis and appropriate medication will be the best way to save the lives of affected ones. The aim of the present study was to determine the bacterial profile of bloodstream infections and their antibiotic susceptibility pattern in Mekelle Hospital. Cross sectional study method was carried out in 514 (269 females and 245 males) febrile patients in Mekelle hospital from March to October 2014. Standard bacteriological methods were used for blood collection, bacterial isolation and antimicrobial susceptibility pattern. Out of the total 514 febrile patients, 144 (28%) culture positive were isolated. Staphylococcus aureus 54 (37.5%), Coagulase-negative staphylococci 44 (30.6%), Escherichia coli 16 (3.1%), Citrobacter spp. 9 (1.7%) and Salmonella typhi 8 (1.6%) were the most dominant isolates, collectively accounting for >90% of the isolates. Antimicrobial resistance pattern for gram positive and gram negative bacteria was 0-83.3% and 0-100%, respectively. High resistance was seen to Trimethoprim-sulphamethoxazole 101 (70.1%), Oxacillin 65 (62.5%), Ceftriaxone 79 (58.9%) and Doxycycline 71 (49.3%). Fifty-nine percent of the isolated bacteria in this study were multi drug resistant. Most bacterial isolates were sensitive to Gentamicin, Ciprofloxacin and Amoxicillin clavulanic acid. All gram positive isolates in this current study were sensitive to vancomycin. Prevalence of bacterial isolates in blood was high. It also reveals isolated bacteria species developed multi drug resistance to most of the antibiotics tested, which highlights for periodic surveillance of etiologic agent, antibiotic susceptibility to prevent further emergence and spread of resistant bacterial pathogens. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 131 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 19% |
| Researcher | 15 | 11% |
| Student > Postgraduate | 13 | 10% |
| Student > Ph. D. Student | 8 | 6% |
| Student > Bachelor | 7 | 5% |
| Other | 22 | 17% |
| Unknown | 41 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 28% |
| Immunology and Microbiology | 11 | 8% |
| Agricultural and Biological Sciences | 10 | 8% |
| Biochemistry, Genetics and Molecular Biology | 9 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 12 | 9% |
| Unknown | 48 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2015.
All research outputs
#20,282,766
of 22,816,807 outputs
Outputs from SpringerPlus
#1,461
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Outputs of similar age
#219,272
of 262,949 outputs
Outputs of similar age from SpringerPlus
#71
of 90 outputs
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