Title |
Prognostic factors in the acute respiratory distress syndrome
|
---|---|
Published in |
Clinical and Translational Medicine, July 2015
|
DOI | 10.1186/s40169-015-0065-2 |
Pubmed ID | |
Authors |
Wei Chen, Lorraine B Ware |
Abstract |
Despite improvements in critical care, acute respiratory distress syndrome (ARDS) remains a devastating clinical problem with high rates of morbidity and mortality. A better understanding of the prognostic factors associated with ARDS is crucial for facilitating risk stratification and developing new therapeutic interventions that aim to improve clinical outcomes. In this article, we present an up-to-date summary of factors that predict mortality in ARDS in four categories: (1) clinical characteristics; (2) physiological parameters and oxygenation; (3) genetic polymorphisms and biomarkers; and (4) scoring systems. In addition, we discuss how a better understanding of clinical and basic pathogenic mechanisms can help to inform prognostication, decision-making, risk stratification, treatment selection, and improve study design for clinical trials. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 21% |
Student > Postgraduate | 6 | 18% |
Student > Bachelor | 5 | 15% |
Other | 3 | 9% |
Student > Master | 2 | 6% |
Other | 5 | 15% |
Unknown | 6 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 20 | 59% |
Nursing and Health Professions | 3 | 9% |
Arts and Humanities | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Sports and Recreations | 1 | 3% |
Other | 1 | 3% |
Unknown | 7 | 21% |