Title |
Increase in intra-abdominal pressure during airway suctioning-induced cough after a successful spontaneous breathing trial is associated with extubation outcome
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Published in |
Annals of Intensive Care, May 2018
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DOI | 10.1186/s13613-018-0410-x |
Pubmed ID | |
Authors |
Yasuhiro Norisue, Jun Kataoka, Yosuke Homma, Takaki Naito, Junpei Tsukuda, Kentaro Okamoto, Takeshi Kawaguchi, Lonny Ashworth, Shimada Yumiko, Yuiko Hoshina, Eiji Hiraoka, Shigeki Fujitani |
Abstract |
A patient's ability to clear secretions and protect the airway with an effective cough is an important part of the pre-extubation evaluation. An increase in intra-abdominal pressure (IAP) is important in generating the flow rate necessary for a cough. This study investigated whether an increase from baseline in IAP during a coughing episode induced by routine pre-extubation airway suctioning is associated with extubation outcome after a successful spontaneous breathing trial (SBT). Three hundred thirty-five (335) mechanically ventilated patients who passed an SBT were enrolled. Baseline IAP and peak IAP during successive suctioning-induced coughs were measured with a fluid column connected to a Foley catheter. Extubation was unsuccessful in 24 patients (7.2%). Unsuccessful extubation was 3.40 times as likely for patients with a delta IAP (ΔIAP) of ≤ 30 cm H2O than for those with a ΔIAP > 30 cm H2O, after adjusting for APACHE II score (95% CI, 1.39-8.26; p = .007). ΔIAP during a coughing episode induced by routine pre-extubation airway suctioning is significantly associated with extubation outcome in patients with a successful SBT. Trial registration UMIN-CTR Clinical Trial, UMIN000017762. Registered 1 June 2015. |
X Demographics
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Australia | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 29 | 100% |
Demographic breakdown
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Other | 4 | 14% |
Student > Doctoral Student | 4 | 14% |
Student > Postgraduate | 4 | 14% |
Student > Master | 4 | 14% |
Researcher | 3 | 10% |
Other | 4 | 14% |
Unknown | 6 | 21% |
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Engineering | 2 | 7% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 0 | 0% |
Unknown | 7 | 24% |