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Atopic dermatitis in West Highland white terriers is associated with a 1.3-Mb region on CFA 17

Overview of attention for article published in Immunogenetics, October 2011
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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2 tweeters

Citations

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Readers on

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27 Mendeley
Title
Atopic dermatitis in West Highland white terriers is associated with a 1.3-Mb region on CFA 17
Published in
Immunogenetics, October 2011
DOI 10.1007/s00251-011-0577-x
Pubmed ID
Authors

Joana B. Roque, Caroline A. O’Leary, David L. Duffy, Myat Kyaw-Tanner, Puya Gharahkhani, Linda Vogelnest, Kenneth Mason, Michael Shipstone, Melanie Latter

Abstract

Canine atopic dermatitis (AD) is an allergic inflammatory skin disease that shares similarities with AD in humans. Canine AD is likely to be an inherited disease in dogs and is common in West Highland white terriers (WHWTs). We performed a genome-wide association study using the Affymetrix Canine SNP V2 array consisting of over 42,800 single nucleotide polymorphisms, on 35 atopic and 25 non-atopic WHWTs. A gene-dropping simulation method, using SIB-PAIR, identified a projected 1.3 Mb area of association (genome-wide P = 6 × 10(-5) to P = 7 × 10(-4)) on CFA 17. Nineteen genes on CFA 17, including 1 potential candidate gene (PTPN22), were located less than 0.5 Mb from the interval of association identified on the genome-wide association analysis. Four haplotypes within this locus were differently distributed between cases and controls in this population of dogs. These findings suggest that a major locus for canine AD in WHWTs may be located on, or in close proximity to an area on CFA 17.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 26%
Researcher 5 19%
Student > Doctoral Student 3 11%
Other 3 11%
Professor 2 7%
Other 7 26%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Agricultural and Biological Sciences 7 26%
Veterinary Science and Veterinary Medicine 6 22%
Biochemistry, Genetics and Molecular Biology 4 15%
Unspecified 2 7%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2011.
All research outputs
#7,635,142
of 12,216,894 outputs
Outputs from Immunogenetics
#848
of 1,048 outputs
Outputs of similar age
#59,484
of 99,750 outputs
Outputs of similar age from Immunogenetics
#3
of 7 outputs
Altmetric has tracked 12,216,894 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,048 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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