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Production of transgenic beef cattle rich in n-3 PUFAs by somatic cell nuclear transfer

Overview of attention for article published in Biotechnology Letters, May 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 1,876)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
9 news outlets
blogs
4 blogs
twitter
10 tweeters
facebook
3 Facebook pages

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
21 Mendeley
Title
Production of transgenic beef cattle rich in n-3 PUFAs by somatic cell nuclear transfer
Published in
Biotechnology Letters, May 2015
DOI 10.1007/s10529-015-1827-z
Pubmed ID
Authors

Gong Cheng, Changzhen Fu, Hong Wang, C. Adoligbe, Shengjuan Wei, Shijun Li, Bijie Jiang, Hongbao Wang, Linsen Zan

Abstract

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are beneficial to human health. However, the n-3 PUFAs contents of the livestock meat that we consume daily are relatively low. Utilization of transgenic technology to increase n-3 PUFAs contents in livestock may solve this problem. The omega-3 fatty acid desaturase (FAD3), encoded by fat1 gene derived from Caenorhabditis elegans (C. elegans), converts omega-6 polyunsaturated fatty acids (n-6 PUFAs) to n-3 PUFAs. In the study, a plasmid containing the codon-optimized C. elegans fat1 gene (mfat1) was constructed and used to produce transgenic beef cattle by somatic cell nuclear transfer. Fourteen transgenic calves were obtained, and the ratio of n-6 to n-3 PUFAs in the transgenic calves decreased from 5.33: 1 to 0.95: 1 compared with negative controls. Our results demonstrated that the codon-optimized C. elegans mfat1 gene can be functionally expressed in the beef cattle and converts n-6 PUFAs to n-3 PUFAs.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Peru 1 5%
Chile 1 5%
Unknown 19 90%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 24%
Student > Ph. D. Student 4 19%
Researcher 3 14%
Unspecified 3 14%
Student > Master 2 10%
Other 4 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 43%
Biochemistry, Genetics and Molecular Biology 3 14%
Unspecified 3 14%
Veterinary Science and Veterinary Medicine 2 10%
Chemistry 2 10%
Other 2 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 104. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2015.
All research outputs
#127,311
of 12,323,844 outputs
Outputs from Biotechnology Letters
#3
of 1,876 outputs
Outputs of similar age
#3,090
of 231,342 outputs
Outputs of similar age from Biotechnology Letters
#1
of 47 outputs
Altmetric has tracked 12,323,844 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,876 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,342 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.