Title |
Sterilization of hydrogen peroxide resistant bacterial spores with stabilized chlorine dioxide
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Published in |
AMB Express, April 2015
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DOI | 10.1186/s13568-015-0109-4 |
Pubmed ID | |
Authors |
Anthony Friedline, Malcolm Zachariah, Amy Middaugh, Matt Heiser, Neeraj Khanna, Parag Vaishampayan, Charles V Rice |
Abstract |
Bacillus pumilus SAFR-032 spores isolated from a clean room environment are known to exhibit enhanced resistance to peroxide, desiccation, UV radiation and chemical disinfection than other spore-forming bacteria. The survival of B. pumilus SAFR-032 spores to standard clean room sterilization practices requires development of more stringent disinfection agents. Here, we report the effects of a stabilized chlorine dioxide-based biocidal agent against spores of B. pumilus SAFR-032 and Bacillus subtilis ATCC 6051. Viability was determined via CFU measurement after exposure. Chlorine dioxide demonstrated efficacy towards sterilization of spores of B. pumilus SAFR-032 equivalent or better than exposure to hydrogen peroxide. These results indicate efficacy of chlorine dioxide delivered through a stabilized chlorine dioxide product as a means of sterilization of peroxide- and UV-resistant spores. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 22% |
Student > Doctoral Student | 5 | 14% |
Researcher | 4 | 11% |
Student > Ph. D. Student | 4 | 11% |
Other | 3 | 8% |
Other | 5 | 14% |
Unknown | 7 | 19% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 8 | 22% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Environmental Science | 3 | 8% |
Chemistry | 3 | 8% |
Immunology and Microbiology | 3 | 8% |
Other | 4 | 11% |
Unknown | 11 | 31% |