| Title |
Characterization of a novel polyclonal anti-hypusine antibody
|
|---|---|
| Published in |
SpringerPlus, August 2013
|
| DOI | 10.1186/2193-1801-2-421 |
| Pubmed ID | |
| Authors |
Yurika Nishiki, Thomas B Farb, Jessica Friedrich, Krister Bokvist, Raghavendra G Mirmira, Bernhard Maier |
| Abstract |
The translation factor eIF5A is the only protein known to contain the amino acid hypusine, which is formed posttranslationally. Hypusinated eIF5A is necessary for cellular proliferation and responses to extracellular stressors, and has been proposed as a target for pharmacologic therapy. Here, we provide the first comprehensive characterization of a novel polyclonal antibody (IU-88) that specifically recognizes the hypusinated eIF5A. IU-88 will be useful for the investigation of eIF5A biology and for the development of assays recognizing hypusinated eIF5A. |
Mendeley readers
The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 37 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 34% |
| Student > Doctoral Student | 4 | 11% |
| Student > Master | 4 | 11% |
| Professor | 3 | 8% |
| Student > Ph. D. Student | 3 | 8% |
| Other | 6 | 16% |
| Unknown | 5 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 34% |
| Agricultural and Biological Sciences | 10 | 26% |
| Immunology and Microbiology | 4 | 11% |
| Medicine and Dentistry | 3 | 8% |
| Chemistry | 2 | 5% |
| Other | 0 | 0% |
| Unknown | 6 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2013.
All research outputs
#15,325,572
of 22,793,427 outputs
Outputs from SpringerPlus
#931
of 1,851 outputs
Outputs of similar age
#123,610
of 199,975 outputs
Outputs of similar age from SpringerPlus
#46
of 89 outputs
Altmetric has tracked 22,793,427 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,851 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,975 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.