Title |
In vitro study of alginate–chitosan microcapsules: an alternative to liver cell transplants for the treatment of liver failure
|
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Published in |
Biotechnology Techniques, March 2005
|
DOI | 10.1007/s10529-005-0687-3 |
Pubmed ID | |
Authors |
Tasima Haque, Hongmei Chen, Wei Ouyang, Christopher Martoni, Bisi Lawuyi, Aleksandra Malgorzata Urbanska, Satya Prakash |
Abstract |
The application of alginate-chitosan (AC) microcapsules to liver cell transplantation has not been previously investigated. In the current in vitro study, we have investigated the potential of AC microcapsules for the encapsulation of liver cells and show that the AC membrane supports the survival, proliferation and protein secretion by entrapped hepatocytes. The AC membrane provides cell immuno-isolation and has the potential for cell cryopreservation. The AC microcapsule has several advantages compared to more widely used alginate-poly-L-lysine (APA) microcapsules for the application of cell therapy. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 2% |
Unknown | 53 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 11 | 20% |
Researcher | 8 | 14% |
Student > Bachelor | 6 | 11% |
Student > Doctoral Student | 2 | 4% |
Other | 6 | 11% |
Unknown | 11 | 20% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 5 | 9% |
Chemistry | 5 | 9% |
Other | 3 | 5% |
Unknown | 14 | 25% |