"Remarkably, in addition to the fast-aging species, the order Rodentia contains multiple long-lived species with lifespans exceeding 20 years (naked mole-rat, beavers, porcupines, and some squirrels)." https://t.co/UYfFX5Y00h
@BillOccham0 @AgingBiology @PLOSGenetics @aubreydegrey @jpsenescence @MattYousefzadeh @philosophising4 @StevenAustad I’ll do you one better: ) https://t.co/Ov8qpSAQn9
@Boldizar @philosophising4 @BakaKarasu @KiesowPaul @lisainbrentwood @GKeeto @KristerKauppi @jsngrdn3 @JaredMichaels17 @mkaeberlein @agingdoc1 @aubreydegrey You’re not even asking the right main question. I.e. «Any reason to suspect that a small/any gero-ex
@jpsenescence @eugediana First we must define «reason» but even rodents age very differently. «In addition to the fast-aging species, the order Rodentia contains multiple long-lived species with lifespans exceeding 20 years (naked mole-rats, beavers, porcu
@Halsted_19 @ArtirKel @StevenAustad And conversely, lifespan can be increased without material halting/reversal of core aging (like say Rapa in mice or physical activity/better diet in old humans). But in rodents any mechanistic lifespan intervention so fa
@aubreydegrey @pfizermule @LauraMinquini @CharlesMBrenner @LongevityTalk @ydeigin Telomerase more active in long-lived rodents: https://t.co/EbhcYxYYW6
@zenobiotic @mkaeberlein @dweinkove @LauraMinquini @eperlste @vita_dao @balajis @realNathanCheng @DrMorganLevine @BrackLab @aubreydegrey @ParrishLiz @ctmurphy1 @davidasinclair Rodent lifespan varies naturally by at least 10x. Manipulating any of the circui
RT @onelifemax: @agingdoc1 genetics/epigenetics/signaling. Fascinating: Rodents for comparative aging studies: from mice to NMR's. https://…
@JohnKelly The body of research is extensive, John. We’re not just guessing here! https://t.co/GLB11KkjuR