| Title |
Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
|
|---|---|
| Published in |
Annals of Intensive Care, December 2017
|
| DOI | 10.1186/s13613-017-0337-7 |
| Pubmed ID | |
| Authors |
Antoine Dewitte, Sébastien Lepreux, Julien Villeneuve, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche |
| Abstract |
Beyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened the spectrum of their role in health and disease. Here, we propose a narrative review that first describes these new platelet attributes. We then examine their relevance to microcirculatory alterations in multi-organ dysfunction, a major sepsis complication. Rapid progresses that are made on the knowledge of novel platelet functions should improve the understanding of thrombocytopenia, a common condition and a predictor of adverse outcome in sepsis, and may provide potential avenues for management and therapy. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 25% |
| United Kingdom | 1 | 25% |
| Denmark | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 239 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 239 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 12% |
| Student > Master | 25 | 10% |
| Student > Postgraduate | 22 | 9% |
| Other | 20 | 8% |
| Researcher | 20 | 8% |
| Other | 48 | 20% |
| Unknown | 76 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 88 | 37% |
| Biochemistry, Genetics and Molecular Biology | 21 | 9% |
| Agricultural and Biological Sciences | 10 | 4% |
| Immunology and Microbiology | 10 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 3% |
| Other | 19 | 8% |
| Unknown | 83 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2023.
All research outputs
#2,146,742
of 23,590,588 outputs
Outputs from Annals of Intensive Care
#264
of 1,074 outputs
Outputs of similar age
#49,527
of 440,469 outputs
Outputs of similar age from Annals of Intensive Care
#3
of 18 outputs
Altmetric has tracked 23,590,588 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,074 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.2. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,469 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.