| Title |
Bioactive compounds from Holothuria atra of Indian ocean
|
|---|---|
| Published in |
SpringerPlus, November 2014
|
| DOI | 10.1186/2193-1801-3-673 |
| Pubmed ID | |
| Authors |
Devaraj Isaac Dhinakaran, Aaron Premnath Lipton |
| Abstract |
The sea cucumber (Holothuria atra) extracts have been evaluated for the presence of bioactive compounds and various biological activities. The methanol extracts showed anti proliferative activities against the Hela and MCF-7 cell lines. Similarly the inhibitory effects of Herpes simplex virus 1 and 2 cells were detected using the plaque reduction assay. The extracts of H. atra were purified using the silica gel column chromatography. The active fractions collected were observed for antimicrobial activity. The GC-MS analysis showed the availability of 59 compounds. The active bioactive compounds found in the H. atra were analyzed and their structure was identified using the (1)HNMR and (13)C NMR experiments. |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Philippines | 1 | 1% |
| Unknown | 86 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 14% |
| Student > Bachelor | 11 | 13% |
| Researcher | 9 | 10% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Other | 16 | 18% |
| Unknown | 23 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 26% |
| Biochemistry, Genetics and Molecular Biology | 16 | 18% |
| Medicine and Dentistry | 6 | 7% |
| Environmental Science | 4 | 5% |
| Chemistry | 4 | 5% |
| Other | 10 | 11% |
| Unknown | 24 | 28% |