Title |
Genetics of Opiate Addiction
|
---|---|
Published in |
Current Psychiatry Reports, September 2014
|
DOI | 10.1007/s11920-014-0504-6 |
Pubmed ID | |
Authors |
Brian Reed, Eduardo R. Butelman, Vadim Yuferov, Matthew Randesi, Mary Jeanne Kreek |
Abstract |
Addiction to MOP-r agonists such as heroin (and also addiction to prescription opioids) has reemerged as an epidemic in the twenty first century, causing massive morbidity. Understanding the genetics contributing to susceptibility to this disease is crucial for the identification of novel therapeutic targets, and also for discovery of genetic markers which would indicate relative protection or vulnerability from addiction, and relative responsiveness to pharmacotherapy. This information could thus eventually inform clinical practice. In this review, we focus primarily on association studies of heroin and opiate addiction, and further describe the studies which have been replicated in this field, and are thus more likely to be useful for translational efforts. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 84 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 21% |
Researcher | 17 | 20% |
Student > Master | 12 | 14% |
Student > Ph. D. Student | 9 | 11% |
Student > Doctoral Student | 5 | 6% |
Other | 7 | 8% |
Unknown | 16 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 20% |
Biochemistry, Genetics and Molecular Biology | 12 | 14% |
Neuroscience | 9 | 11% |
Nursing and Health Professions | 9 | 11% |
Psychology | 7 | 8% |
Other | 11 | 13% |
Unknown | 19 | 23% |