@jd_wilko Large margins common in oncology Lot easier to parallel park in a space the size of a schoolbus https://t.co/CCx3ixbIip
RT @VPrasadMDMPH: Devastating comment about a bad Noninferiority trial @drjohnm 👇 Mixing these endpoints is madness Wrote an explainer on…
RT @VPrasadMDMPH: Devastating comment about a bad Noninferiority trial @drjohnm 👇 Mixing these endpoints is madness Wrote an explainer on…
RT @VPrasadMDMPH: Devastating comment about a bad Noninferiority trial @drjohnm 👇 Mixing these endpoints is madness Wrote an explainer on…
RT @VPrasadMDMPH: Devastating comment about a bad Noninferiority trial @drjohnm 👇 Mixing these endpoints is madness Wrote an explainer on…
Devastating comment about a bad Noninferiority trial @drjohnm 👇 Mixing these endpoints is madness Wrote an explainer on non-inferiority here https://t.co/CCx3iwTz4h
Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? - PubMed https://t.co/aQQ0KwaD5g
@JamesBatesMD @Rad_Nation @AndrearicFili And perhaps for those still learning stats (like me), a refresh on how non-inferiority trials stack up (and why some double negatives may make more sense) https://t.co/kymY2tMW4V v @NephJC @manasib33 https://t.co
@paulpharoah @TomPMarshall @VictorDayan1 In 2017, @VPrasadMDMPH wrote an editorial 'Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy?' https://t.co/9ke4pewiEL
Oops! Vinay Prasad, Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? https://t.co/vqTvOL6SlD
@Barbusceptique Prasad, à la fin de son article https://t.co/j8zy7slrcF établit une sorte de check-list pour les praticiens afin qu'ils puissent analyser la qualité d'une étude, des questions clés pour s'orienter. On pourrait réfléchir à élaborer une sorte
RT @VPrasadMDMPH: If you want to read more about bad noninferiority trials, read this https://t.co/L8KOrs3OFv https://t.co/9vvINM66K5
RT @MartinFierro769: 5/n C'est un problème de définition et de cohérence. Le manque de cohérence est du côté des recommandations CONSORT po…
5/n C'est un problème de définition et de cohérence. Le manque de cohérence est du côté des recommandations CONSORT pour l'interprétation des essais cliniques comme l'explique Vinay Prasad ici https://t.co/oH2TAI3V3W
Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? | SpringerLink https://t.co/L4vdp2HMDC
RT @pash22: Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? https://t.co/9ke4pewiEL via @VPrasadMDMPH
Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? https://t.co/9ke4pewiEL via @VPrasadMDMPH
@ajumathew_ @VPrasadMDMPH @venkymd @drnirmalraut @venkmurthy @THilalMD @hswapnil And Vinay @VPrasadMDMPH commented on this on twitter https://t.co/vbPwi9zVTS
RT @ProfDFrancis: Shrewd article from Vinay Prasad on what to consider when reading a non-inferiority trial. If interest, I can cover this…
RT @LanceShaver: @ConnPharmIntern @tldrpharmacy Great addition on Superiority vs non-inferiority trials. Liked Dr. Prasad's editorial on th…
@ConnPharmIntern @tldrpharmacy Great addition on Superiority vs non-inferiority trials. Liked Dr. Prasad's editorial on the pitfalls of non-inferiority trials https://t.co/cp3zBoSVqX
RT @MartinFierro769: Pour comprendre pourquoi les essais de non infériorité, systématiquement utilisés avec l'aval des agences de régulatio…
RT @MartinFierro769: Pour comprendre pourquoi les essais de non infériorité, systématiquement utilisés avec l'aval des agences de régulatio…
Pour comprendre pourquoi les essais de non infériorité, systématiquement utilisés avec l'aval des agences de régulation pour introduire de nouvelles molécules, doivent être pris avec des pincettes, un article de Vinay Prasad https://t.co/oH2TAI3V3W https:/
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @ProfDFrancis: Shrewd article from Vinay Prasad on what to consider when reading a non-inferiority trial. If interest, I can cover this…
Yet another publication, and one more data point confirming that @VinayPrasadMD does not sleep. https://t.co/wtu8TY1alF
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @yachu93: Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? https://t.co/RoGwwfQSlJ
Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? https://t.co/RoGwwfQSlJ
And I kept forgetting where I read this whole NI thing on twitter few weeks ago. It’s here, NI trials in medicine by @VinayPrasadMD https://t.co/u5ETSY12bn
RT @DrRitaMc: #MedEd #GrainOfSalt #trialdesign #outcomes Non-inferiority trials... an inferior RCT structure? @amtejani @Drug_Evidence @…
RT @DrRitaMc: #MedEd #GrainOfSalt #trialdesign #outcomes Non-inferiority trials... an inferior RCT structure? @amtejani @Drug_Evidence @…
"Non-inferiority trials are often positive because the margins are chosen for no clearly given reason . . ." https://t.co/jVVd6KXHMP
RT @DrRitaMc: #MedEd #GrainOfSalt #trialdesign #outcomes Non-inferiority trials... an inferior RCT structure? @amtejani @Drug_Evidence @…
#MedEd #GrainOfSalt #trialdesign #outcomes Non-inferiority trials... an inferior RCT structure? @amtejani @Drug_Evidence @AKECassels https://t.co/DKUhkvfjzF
RT @Vilavaite: "When you read a non-inferiority #trial ask yourself: Is the new #therapy cheaper, more convenient, less invasive, or less t…
RT @Vilavaite: "When you read a non-inferiority #trial ask yourself: Is the new #therapy cheaper, more convenient, less invasive, or less t…
RT @Vilavaite: "When you read a non-inferiority #trial ask yourself: Is the new #therapy cheaper, more convenient, less invasive, or less t…
RT @Vilavaite: "When you read a non-inferiority #trial ask yourself: Is the new #therapy cheaper, more convenient, less invasive, or less t…
RT @chowkydar: @efunkEM @VinayPrasad82's skeptical take here: https://t.co/6G5531z2Tr
RT @chowkydar: @efunkEM @VinayPrasad82's skeptical take here: https://t.co/6G5531z2Tr
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RogueRad: Clear explanation of non inferior trials by @VinayPrasad82., which seem like RCT's version of participation trophies https://…
Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy? | SpringerLink https://t.co/8ZIAPEuvdd
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
Great editorial on how NIT are poorly executed + exploited. Good use = eval if lifestyle interventions w/ fewer AE (but less convenient than taking a pill?) equiv to BPH/OAB meds in older men. Choosing margin still hard for QOL but min detectable diff =goo
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @jpbettger: Agree - great editorial on non-inferiority trials. "Ask yourself, is the new therapy cheaper, > convenient, < invasive, or…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @rafeeq_rm: Everyone practicing medicine should understand these concepts explained in this paper https://t.co/VZ2oDiAUbF #non-inferiori…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
Interesting read https://t.co/zTjNgXqD02
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
An unsettling insight into the poor methodology and unethical conduct of many non-inferiority trials in #medicine. #MedChat #MedEd #Pharmacy #clinicaltrials https://t.co/XM56IHzltt
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
Everyone practicing medicine should understand these concepts explained in this paper https://t.co/VZ2oDiAUbF #non-inferiority trials may not add much value to patient’s needs. Very relevant in #IBD
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @geri_doc: Non-inferiority trials in medicine: Practice changing or a self-fulfilling prophesy? Excellent editorial. Non-inferiority…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @jpbettger: Agree - great editorial on non-inferiority trials. "Ask yourself, is the new therapy cheaper, > convenient, < invasive, or…
Agree - great editorial on non-inferiority trials. "Ask yourself, is the new therapy cheaper, > convenient, < invasive, or < toxic than the other? If not, read no further." https://t.co/o1tUCN68Y5
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…
RT @RichardLehman1: "Non-inferiority trials only make sense if the experimental therapy is cheaper, more convenient, less invasive, or less…