| Title |
Effects of some anesthetic agents on skin microcirculation evaluated by laser Doppler perfusion imaging in mice
|
|---|---|
| Published in |
BMC Veterinary Research, December 2013
|
| DOI | 10.1186/1746-6148-9-255 |
| Pubmed ID | |
| Authors |
Sara Gargiulo, Matteo Gramanzini, Raffaele Liuzzi, Adelaide Greco, Arturo Brunetti, Giancarlo Vesce |
| Abstract |
Anesthetic agents alter microcirculation, influencing tissue oxygenation and delivery of vital substrates. Laser Doppler perfusion imaging is a widespread technique in the field of microvascular research that can evaluate noninvasively and in real time the effects of environmental conditions, physical manipulations, diseases and treatments on peripheral perfusion. This study aims to evaluate laser Doppler perfusion imaging as a means to detect changes in skin microcirculation induced by some popular anesthetic agents in a murine model. Twenty-four age- and gender-matched healthy CD1 mice were examined by laser Doppler perfusion imaging. The skin microcirculatory response was measured at the level of plantar surfaces during isoflurane anesthesia with or without subsequent dexmedetomidine or acepromazine. At the end of the procedure, dexmedetomidine was reversed by atipamezole administration. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 3% |
| Unknown | 32 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 30% |
| Other | 3 | 9% |
| Student > Master | 3 | 9% |
| Student > Bachelor | 3 | 9% |
| Student > Ph. D. Student | 2 | 6% |
| Other | 6 | 18% |
| Unknown | 6 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 27% |
| Veterinary Science and Veterinary Medicine | 5 | 15% |
| Agricultural and Biological Sciences | 3 | 9% |
| Engineering | 3 | 9% |
| Neuroscience | 2 | 6% |
| Other | 5 | 15% |
| Unknown | 6 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2014.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from BMC Veterinary Research
#2,106
of 3,298 outputs
Outputs of similar age
#235,172
of 307,714 outputs
Outputs of similar age from BMC Veterinary Research
#42
of 55 outputs
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