Title |
Personalized predictive lung dosimetry by technetium-99m macroaggregated albumin SPECT/CT for yttrium-90 radioembolization
|
---|---|
Published in |
EJNMMI Research, June 2014
|
DOI | 10.1186/s13550-014-0033-7 |
Pubmed ID | |
Authors |
Yung Hsiang Kao, Butch M Magsombol, Ying Toh, Kiang Hiong Tay, Pierce KH Chow, Anthony SW Goh, David CE Ng |
Abstract |
For yttrium-90 ((90)Y) radioembolization, the common practice of assuming a standard 1,000-g lung mass for predictive dosimetry is fundamentally incongruent with the modern philosophy of personalized medicine. We recently developed a technique of personalized predictive lung dosimetry using technetium-99m ((99m)Tc) macroaggregated albumin (MAA) single photon emission computed tomography with integrated CT (SPECT/CT) of the lung as part of our routine dosimetric protocol for (90)Y radioembolization. Its rationales are the technical superiority of SPECT/CT over planar scintigraphy, ease and convenience of lung auto-segmentation CT densitovolumetry, and dosimetric advantage of patient-specific lung parenchyma masses. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 64 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 20% |
Researcher | 12 | 19% |
Student > Doctoral Student | 6 | 9% |
Professor | 4 | 6% |
Student > Bachelor | 4 | 6% |
Other | 13 | 20% |
Unknown | 12 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 38% |
Physics and Astronomy | 12 | 19% |
Engineering | 4 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Social Sciences | 2 | 3% |
Other | 4 | 6% |
Unknown | 16 | 25% |