| Title |
Intestinal perforation after nivolumab immunotherapy for a malignant melanoma: a case report
|
|---|---|
| Published in |
Surgical Case Reports, August 2017
|
| DOI | 10.1186/s40792-017-0370-7 |
| Pubmed ID | |
| Authors |
Koji Yasuda, Toshiaki Tanaka, Soichiro Ishihara, Kensuke Otani, Takeshi Nishikawa, Tomomichi Kiyomatsu, Kazushige Kawai, Keisuke Hata, Hiroaki Nozawa, Yuri Masui, Yukako Shintani, Toshiaki Watanabe |
| Abstract |
Nivolumab is a monoclonal antibody against programmed death 1 and has become a standard treatment of advanced melanoma because of its durable response and survival benefits. In this report, we present a case of severe intestinal perforation after nivolumab immunotherapy for malignant melanoma. A 73-year-old man with stage IV malignant melanoma underwent nivolumab therapy. The patient presented to our hospital because of a progressing abdominal pain. Radiological evaluation revealed evidence of free intraperitoneal air. Therefore, we diagnosed the patient as having an intestinal perforation, which was successfully resolved after surgical treatment. Although intestinal perforation after nivolumab immunotherapy is rare, it can be severe and requires early diagnosis and emergency surgery to ensure a favorable prognosis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 22% |
| Professor > Associate Professor | 1 | 11% |
| Unspecified | 1 | 11% |
| Lecturer | 1 | 11% |
| Other | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 3 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 33% |
| Biochemistry, Genetics and Molecular Biology | 1 | 11% |
| Unspecified | 1 | 11% |
| Unknown | 4 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2019.
All research outputs
#7,340,078
of 23,866,543 outputs
Outputs from Surgical Case Reports
#22
of 523 outputs
Outputs of similar age
#112,567
of 318,384 outputs
Outputs of similar age from Surgical Case Reports
#1
of 10 outputs
Altmetric has tracked 23,866,543 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 523 research outputs from this source. They receive a mean Attention Score of 0.9. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them