Title |
“Bicellar” Lipid Mixtures as used in Biochemical and Biophysical Studies
|
---|---|
Published in |
The Science of Nature, July 2005
|
DOI | 10.1007/s00114-005-0641-1 |
Pubmed ID | |
Authors |
John Katsaras, Thad A. Harroun, Jeremy Pencer, Mu-Ping Nieh |
Abstract |
Over the past decade "bicellar" lipid mixtures composed of the long-chain dimyristoyl phosphatidylcholine (DMPC) and the short-chain dihexanoyl PC (DHPC) molecules have emerged as a powerful medium for studying membrane associated, biologically relevant macromolecules and assemblies. Depending on temperature, lipid concentration and composition these lipid mixtures can assume a variety of morphologies, some of them alignable in the presence of a magnetic field. This article will examine the biophysical studies that have elucidated the various morphologies assumed by these lipid mixtures, and their use in the biochemical studies of biomolecules. |
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