| Title |
Characterization of a novel cell penetrating peptide derived from human Oct4
|
|---|---|
| Published in |
Cell Regeneration, January 2014
|
| DOI | 10.1186/2045-9769-3-2 |
| Pubmed ID | |
| Authors |
Eva Harreither, Hanna A Rydberg, Helene L Åmand, Vaibhav Jadhav, Lukas Fliedl, Christina Benda, Miguel A Esteban, Duanqing Pei, Nicole Borth, Regina Grillari-Voglauer, Oliver Hommerding, Frank Edenhofer, Bengt Nordén, Johannes Grillari |
| Abstract |
Oct4 is a transcription factor that plays a major role for the preservation of the pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic cells to induced pluripotent stem cells (iPSC) or other progenitors. Protein-based reprogramming methods mainly rely on the addition of a fused cell penetrating peptide. This study describes that Oct4 inherently carries a protein transduction domain, which can translocate into human and mouse cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 1% |
| Uruguay | 1 | 1% |
| Austria | 1 | 1% |
| Japan | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 72 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 23% |
| Researcher | 15 | 19% |
| Student > Master | 10 | 13% |
| Professor > Associate Professor | 7 | 9% |
| Student > Bachelor | 5 | 6% |
| Other | 14 | 18% |
| Unknown | 8 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 43% |
| Biochemistry, Genetics and Molecular Biology | 17 | 22% |
| Chemistry | 6 | 8% |
| Medicine and Dentistry | 4 | 5% |
| Engineering | 2 | 3% |
| Other | 4 | 5% |
| Unknown | 11 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2014.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Cell Regeneration
#133
of 189 outputs
Outputs of similar age
#244,325
of 322,359 outputs
Outputs of similar age from Cell Regeneration
#3
of 3 outputs
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So far Altmetric has tracked 189 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
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