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| Title |
Lifetime eating disorder comorbidity associated with delayed depressive recovery in bipolar disorder
|
|---|---|
| Published in |
International Journal of Bipolar Disorders, August 2017
|
| DOI | 10.1186/s40345-017-0094-4 |
| Pubmed ID | |
| Authors |
Danielle R. Balzafiore, Natalie L. Rasgon, Laura D. Yuen, Saloni Shah, Hyun Kim, Kathryn C. Goffin, Shefali Miller, Po W. Wang, Terence A. Ketter |
| Abstract |
Although eating disorders (EDs) are common in bipolar disorder (BD), little is known regarding their longitudinal consequences. We assessed prevalence, clinical correlates, and longitudinal depressive severity in BD patients with vs. without EDs. Outpatients referred to Stanford University BD Clinic during 2000-2011 were assessed with the Systematic Treatment Enhancement Program for BD (STEP-BD) affective disorders evaluation, and while receiving naturalistic treatment for up to 2 years, were monitored with the STEP-BD clinical monitoring form. Patients with vs. without lifetime EDs were compared with respect to prevalence, demographic and unfavorable illness characteristics/current mood symptoms and psychotropic use, and longitudinal depressive severity. Among 503 BD outpatients, 76 (15.1%) had lifetime EDs, which were associated with female gender, and higher rates of lifetime comorbid anxiety, alcohol/substance use, and personality disorders, childhood BD onset, episode accumulation (≥10 prior mood episodes), prior suicide attempt, current syndromal/subsyndromal depression, sadness, anxiety, and antidepressant use, and earlier BD onset age, and greater current overall BD severity. Among currently depressed patients, 29 with compared to 124 without lifetime EDs had significantly delayed depressive recovery. In contrast, among currently recovered (euthymic ≥8 weeks) patients, 10 with compared to 95 without lifetime EDs had only non-significantly hastened depressive recurrence. Primarily Caucasian, insured, suburban, American specialty clinic-referred sample limits generalizability. Small number of recovered patients with EDs limited statistical power to detect relationships between EDs and depressive recurrence. Further studies are warranted to explore the degree to which EDs impact longitudinal depressive illness burden in BD. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 13% |
| Student > Postgraduate | 8 | 13% |
| Researcher | 8 | 13% |
| Student > Bachelor | 7 | 11% |
| Other | 3 | 5% |
| Other | 6 | 10% |
| Unknown | 23 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 17 | 27% |
| Medicine and Dentistry | 10 | 16% |
| Neuroscience | 3 | 5% |
| Social Sciences | 2 | 3% |
| Nursing and Health Professions | 1 | 2% |
| Other | 4 | 6% |
| Unknown | 26 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2017.
All research outputs
#14,345,967
of 22,971,207 outputs
Outputs from International Journal of Bipolar Disorders
#196
of 285 outputs
Outputs of similar age
#176,976
of 318,602 outputs
Outputs of similar age from International Journal of Bipolar Disorders
#5
of 11 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 285 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.1. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,602 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.