| Title |
Cognitive remediation for bipolar patients with objective cognitive impairment: a naturalistic study
|
|---|---|
| Published in |
International Journal of Bipolar Disorders, April 2017
|
| DOI | 10.1186/s40345-017-0079-3 |
| Pubmed ID | |
| Authors |
J. Veeh, J. Kopf, S. Kittel-Schneider, J. Deckert, A. Reif |
| Abstract |
Many bipolar patients (BP) are affected by cognitive impairments and reduced psychosocial function even after complete remission. In the present naturalistic study, we developed a tailored cognitive remediation program (CR) to evaluate the effect on objective and subjective neuropsychological performance, psychosocial functioning and quality of life. The CR program used a cognitive training software combined with group sessions to educate cognitive skills. 102 BP were screened by a neuropsychological test battery. Of those, 39 BP showed distinct cognitive impairments and 26 patients of them participated in the CR program for 12 weeks and then were retested. A matched control group consisting of 10 BP was measured at baseline and follow-up after three months (treatment as usual). Within the training group, a significant improvement of cognitive performance after CR was observed in working memory (p = .043), problem solving (p = .031) and divided attention (trend, p = .065). The control group did not improve in any test measure. In addition, we detected a significant reduction of sub-depressive symptoms (p = .011) after the CR program. However, there was no change in psychosocial functioning and quality of life. Subjective cognitive complaints were not associated with objective test performance. As we included exclusively BP with objectively assessed neurocognitive deficits, recruitment was difficult and subsequently we had a small sample size and were not able to implement a randomized group design. Our results suggest that BP with objective cognitive impairments could benefit from CR potentially with regard to executive functioning. Furthermore, there is preliminary evidence that CR could have a positive effect on subthreshold residual symptoms. However, to fully identify the possible implications of CR in bipolar disorder, larger randomized-controlled trials are needed in this new field of research. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 20% |
| Germany | 1 | 20% |
| Portugal | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 108 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 18% |
| Student > Bachelor | 15 | 14% |
| Researcher | 9 | 8% |
| Student > Ph. D. Student | 8 | 7% |
| Student > Postgraduate | 6 | 6% |
| Other | 23 | 21% |
| Unknown | 28 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 30 | 28% |
| Neuroscience | 14 | 13% |
| Medicine and Dentistry | 12 | 11% |
| Nursing and Health Professions | 7 | 6% |
| Business, Management and Accounting | 2 | 2% |
| Other | 11 | 10% |
| Unknown | 32 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2017.
All research outputs
#2,457,402
of 23,508,125 outputs
Outputs from International Journal of Bipolar Disorders
#63
of 291 outputs
Outputs of similar age
#47,754
of 311,128 outputs
Outputs of similar age from International Journal of Bipolar Disorders
#2
of 10 outputs
Altmetric has tracked 23,508,125 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 291 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has done well, scoring higher than 78% of its peers.
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We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.