| Title |
Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses
|
|---|---|
| Published in |
Virologica Sinica, April 2017
|
| DOI | 10.1007/s12250-016-3930-2 |
| Pubmed ID | |
| Authors |
Cecilia Waruhiu, Sheila Ommeh, Vincent Obanda, Bernard Agwanda, Francis Gakuya, Xing-Yi Ge, Xing-Lou Yang, Li-Jun Wu, Ali Zohaib, Ben Hu, Zheng-Li Shi |
| Abstract |
This is the first country-wide surveillance of bat-borne viruses in Kenya spanning from 2012-2015 covering sites perceived to have medium to high level bat-human interaction. The objective of this surveillance study was to apply a non-invasive approach using fresh feces to detect viruses circulating within the diverse species of Kenyan bats. We screened for both DNA and RNA viruses; specifically, astroviruses (AstVs), adenoviruses (ADVs), caliciviruses (CalVs), coronaviruses (CoVs), flaviviruses, filoviruses, paramyxoviruses (PMVs), polyomaviruses (PYVs) and rotaviruses. We used family-specific primers, amplicon sequencing and further characterization by phylogenetic analysis. Except for filoviruses, eight virus families were detected with varying distributions and positive rates across the five regions (former provinces) studied. AstVs (12.83%), CoVs (3.97%), PMV (2.4%), ADV (2.26%), PYV (1.65%), CalVs (0.29%), rotavirus (0.19%) and flavivirus (0.19%). Novel CalVs were detected in Rousettus aegyptiacus and Mops condylurus while novel Rotavirus-A-related viruses were detected in Taphozous bats and R. aegyptiacus. The two Rotavirus A (RVA) strains detected were highly related to human strains with VP6 genotypes I2 and I16. Genotype I16 has previously been assigned to human RVA-strain B10 from Kenya only, which raises public health concern, particularly considering increased human-bat interaction. Additionally, 229E-like bat CoVs were detected in samples originating from Hipposideros bats roosting in sites with high human activity. Our findings confirm the presence of diverse viruses in Kenyan bats while providing extended knowledge on bat virus distribution. The detection of viruses highly related to human strains and hence of public health concern, underscores the importance of continuous surveillance. |
X Demographics
The data shown below were collected from the profiles of 103 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Kenya | 35 | 34% |
| United States | 5 | 5% |
| New Zealand | 2 | 2% |
| South Africa | 2 | 2% |
| France | 2 | 2% |
| Belgium | 1 | <1% |
| India | 1 | <1% |
| Vietnam | 1 | <1% |
| Taiwan | 1 | <1% |
| Other | 3 | 3% |
| Unknown | 50 | 49% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 98 | 95% |
| Scientists | 3 | 3% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 107 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 23% |
| Researcher | 17 | 16% |
| Student > Ph. D. Student | 10 | 9% |
| Student > Bachelor | 8 | 7% |
| Student > Doctoral Student | 5 | 5% |
| Other | 13 | 12% |
| Unknown | 29 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 22% |
| Biochemistry, Genetics and Molecular Biology | 17 | 16% |
| Veterinary Science and Veterinary Medicine | 11 | 10% |
| Environmental Science | 6 | 6% |
| Computer Science | 3 | 3% |
| Other | 11 | 10% |
| Unknown | 35 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 85. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#511,921
of 25,703,943 outputs
Outputs from Virologica Sinica
#14
of 678 outputs
Outputs of similar age
#10,565
of 325,522 outputs
Outputs of similar age from Virologica Sinica
#1
of 11 outputs
Altmetric has tracked 25,703,943 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 678 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has done particularly well, scoring higher than 97% of its peers.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.