Title |
Intra-operative radiological margins assessment in conservative treatment for non-palpable DCIS: correlation to pathological examination and re-excision rate
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Published in |
SpringerPlus, May 2013
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DOI | 10.1186/2193-1801-2-243 |
Pubmed ID | |
Authors |
Federico Buggi, Matteo Mingozzi, Annalisa Curcio, Camilla Rossi, Oriana Nanni, Lucia Bedei, Paola A Sanna, Salvatore Veltri, Secondo Folli |
Abstract |
What constitutes an adequate surgical margin in partial mastectomy is still controversial: intra-operative specimen radiogram is commonly used during partial mastectomy for nonpalpable lesions in order verify the adequacy of the resection but what margin is to be considered "adequate" is still debatable. An intraoperative specimen mammogram was performed during all consecutive conservative resections for nonpalpable DCIS and a 15-mm radiological margin was considered "adequate". Margins were pathologically assessed and classified as "negative", "close" or "positive" and the rate of margin involvement constitued the main outcome of the study. Among 272 conservative interventions, 80.51% had negative margins at final pathology, 3.31% had close margins and 16.18% had positive margins. An intraoperative "adequate" margin of 15 mm as defined on intraoperative specimen mammogram granted a high rate of histologically negative margin at primary surgery; this finding was paralleled by confirmation of the treatment as conservative in 95% of cases. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 2 | 22% |
Student > Ph. D. Student | 2 | 22% |
Other | 1 | 11% |
Student > Doctoral Student | 1 | 11% |
Professor | 1 | 11% |
Other | 2 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 56% |
Biochemistry, Genetics and Molecular Biology | 1 | 11% |
Business, Management and Accounting | 1 | 11% |
Engineering | 1 | 11% |
Unknown | 1 | 11% |