| Title |
Antibiotic stewardship in the ICU: time to shift into overdrive
|
|---|---|
| Published in |
Annals of Intensive Care, May 2023
|
| DOI | 10.1186/s13613-023-01134-9 |
| Pubmed ID | |
| Authors |
David Mokrani, Juliette Chommeloux, Marc Pineton de Chambrun, Guillaume Hékimian, Charles-Edouard Luyt |
| Abstract |
Antibiotic resistance is a major health problem and will be probably one of the leading causes of deaths in the coming years. One of the most effective ways to fight against resistance is to decrease antibiotic consumption. Intensive care units (ICUs) are places where antibiotics are widely prescribed, and where multidrug-resistant pathogens are frequently encountered. However, ICU physicians may have opportunities to decrease antibiotics consumption and to apply antimicrobial stewardship programs. The main measures that may be implemented include refraining from immediate prescription of antibiotics when infection is suspected (except in patients with shock, where immediate administration of antibiotics is essential); limiting empiric broad-spectrum antibiotics (including anti-MRSA antibiotics) in patients without risk factors for multidrug-resistant pathogens; switching to monotherapy instead of combination therapy and narrowing spectrum when culture and susceptibility tests results are available; limiting the use of carbapenems to extended-spectrum beta-lactamase-producing Enterobacteriaceae, and new beta-lactams to difficult-to-treat pathogen (when these news beta-lactams are the only available option); and shortening the duration of antimicrobial treatment, the use of procalcitonin being one tool to attain this goal. Antimicrobial stewardship programs should combine these measures rather than applying a single one. ICUs and ICU physicians should be at the frontline for developing antimicrobial stewardship programs. |
X Demographics
The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 4 | 12% |
| Spain | 3 | 9% |
| Chile | 2 | 6% |
| Peru | 1 | 3% |
| Ecuador | 1 | 3% |
| Colombia | 1 | 3% |
| Vietnam | 1 | 3% |
| Argentina | 1 | 3% |
| France | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 16 | 48% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 26 | 79% |
| Practitioners (doctors, other healthcare professionals) | 5 | 15% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
| Scientists | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 51 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 6 | 12% |
| Other | 5 | 10% |
| Student > Bachelor | 5 | 10% |
| Student > Postgraduate | 3 | 6% |
| Lecturer | 2 | 4% |
| Other | 10 | 20% |
| Unknown | 20 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 35% |
| Unspecified | 6 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 10% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Immunology and Microbiology | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 19 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2024.
All research outputs
#1,972,986
of 25,713,737 outputs
Outputs from Annals of Intensive Care
#245
of 1,210 outputs
Outputs of similar age
#38,805
of 405,663 outputs
Outputs of similar age from Annals of Intensive Care
#7
of 29 outputs
Altmetric has tracked 25,713,737 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,210 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 405,663 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.