| Title |
Efficient surface functionalization of wound dressings by a phytoactive nanocoating refractory to Candida albicans biofilm development
|
|---|---|
| Published in |
Biointerphases, April 2013
|
| DOI | 10.1186/1559-4106-8-12 |
| Pubmed ID | |
| Authors |
Ion Anghel, Alina Maria Holban, Ecaterina Andronescu, Alexandru Mihai Grumezescu, Mariana Carmen Chifiriuc |
| Abstract |
The present study reports the fabrication and characterization of a novel nanostructured phyto-bioactive coated rayon/polyester wound dressing (WD) surface refractory to Candida albicans adhesion, colonization and biofilm formation, based on functionalized magnetite nanoparticles and Anethum graveolens (AG) and Salvia officinalis (SO) essential oils (EOs). TEM, XRD, TGA, FT-IR were used for the characterization of the fabricated nanobiocoated WDs. Using magnetic nanoparticles for the stabilization and controlled release of EOs, the activity of natural volatile compounds is significantly enhanced and their effect is stable during time. For this reason the nanobiocoated surfaces exhibited a longer term anti-biofilm effect, maintained for at least 72 h. Besides their excellent anti- adherence properties, the proposed solutions exhibit the advantage of using vegetal natural compounds, which are less toxic and easily biodegradable in comparison with synthetic antifungal drugs, representing thus promising approaches for the development of successful ways to control and prevent fungal biofilms associated infections. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 50 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 10 | 20% |
| Student > Ph. D. Student | 7 | 14% |
| Student > Master | 7 | 14% |
| Researcher | 6 | 12% |
| Student > Doctoral Student | 3 | 6% |
| Other | 10 | 20% |
| Unknown | 7 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 20% |
| Unspecified | 7 | 14% |
| Immunology and Microbiology | 3 | 6% |
| Engineering | 3 | 6% |
| Medicine and Dentistry | 3 | 6% |
| Other | 9 | 18% |
| Unknown | 15 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2015.
All research outputs
#15,075,877
of 23,942,155 outputs
Outputs from Biointerphases
#313
of 544 outputs
Outputs of similar age
#113,052
of 196,659 outputs
Outputs of similar age from Biointerphases
#1
of 1 outputs
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So far Altmetric has tracked 544 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
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