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Title |
Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection
|
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Published in |
Critical Care, August 2010
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DOI | 10.1186/cc9051 |
Pubmed ID | |
Authors |
Robert Dickinson, Nicholas P Franks |
Abstract |
In the past decade there has been a resurgence of interest in the clinical use of inert gases. In the present paper we review the use of inert gases as anesthetics and neuroprotectants, with particular attention to the clinical use of xenon. We discuss recent advances in understanding the molecular pharmacology of xenon and we highlight specific pharmacological targets that may mediate its actions as an anesthetic and neuroprotectant. We summarize recent in vitro and in vivo studies on the actions of helium and the other inert gases, and discuss their potential to be used as neuroprotective agents. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Brazil | 1 | 1% |
Czechia | 1 | 1% |
Canada | 1 | 1% |
Peru | 1 | 1% |
Belgium | 1 | 1% |
Russia | 1 | 1% |
Unknown | 81 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 17% |
Researcher | 15 | 17% |
Student > Master | 9 | 10% |
Student > Bachelor | 9 | 10% |
Student > Doctoral Student | 6 | 7% |
Other | 22 | 25% |
Unknown | 13 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 46% |
Neuroscience | 12 | 13% |
Agricultural and Biological Sciences | 9 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Physics and Astronomy | 3 | 3% |
Other | 6 | 7% |
Unknown | 15 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2022.
All research outputs
#3,025,940
of 25,373,627 outputs
Outputs from Critical Care
#2,527
of 6,554 outputs
Outputs of similar age
#11,741
of 104,289 outputs
Outputs of similar age from Critical Care
#8
of 35 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,289 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.