| Title |
Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers
|
|---|---|
| Published in |
Cancer Chemotherapy and Pharmacology, May 2011
|
| DOI | 10.1007/s00280-011-1673-1 |
| Pubmed ID | |
| Authors |
Masashi Kanai, Atsushi Imaizumi, Yoshihiko Otsuka, Hiroki Sasaki, Momo Hashiguchi, Kazu Tsujiko, Shigemi Matsumoto, Hiroshi Ishiguro, Tsutomu Chiba |
| Abstract |
More and more preclinical studies support the idea that curcumin, a plant-derived natural polyphenol, could be a promising anticancer drug. However, poor bioavailability has limited its efficacy in clinical trials, and plasma curcumin levels remain low despite patients taking gram doses of curcumin. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 217 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 35 | 16% |
| Student > Ph. D. Student | 34 | 16% |
| Researcher | 23 | 11% |
| Student > Bachelor | 19 | 9% |
| Other | 13 | 6% |
| Other | 46 | 21% |
| Unknown | 49 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 17% |
| Agricultural and Biological Sciences | 29 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 26 | 12% |
| Biochemistry, Genetics and Molecular Biology | 17 | 8% |
| Chemistry | 12 | 5% |
| Other | 40 | 18% |
| Unknown | 57 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2021.
All research outputs
#644,792
of 23,815,455 outputs
Outputs from Cancer Chemotherapy and Pharmacology
#10
of 2,501 outputs
Outputs of similar age
#2,267
of 113,584 outputs
Outputs of similar age from Cancer Chemotherapy and Pharmacology
#1
of 20 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,501 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,584 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.