Title |
Endoscopic resection versus surgery for early gastric cancer and precancerous lesions: a meta-analysis
|
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Published in |
SpringerPlus, May 2016
|
DOI | 10.1186/s40064-016-2273-7 |
Pubmed ID | |
Authors |
Shulei Zhao, Xiaohua Zhang, Jing Wang, Jian Ge, Jin Liu |
Abstract |
To compare the efficacy and safety of endoscopic resection (ER) and surgery for the treatment of early gastric cancer and precancerous lesions. Databases, such as PubMed, EMBASE, Cochrane Library, and Science Citation Index, from 2000 to 2016, were searched for eligible articles. In this meta-analysis, the main outcome measurements were local recurrence, complications, metachronous lesions, hospital stay, and 5-year overall survival. Nine trials were identified and a total of 2748 patients were included. The rate of complication was higher in the surgery group compared with the ER group (OR 0.41; 95 % CI 0.30-0.55). The rates of local recurrence and metachronous lesions were lower in the surgery group (OR 0.03; 95 % CI 0.00-0.06; OR 8.76; 95 % CI 4.17-18.41). The hospital stay was shorter in the ER group (mean difference -6.96; 95 % CI -7.94 to -5.99). The 5-year overall survival rate did not significantly differ between the two groups (OR 1.23; 95 % CI 1.03-1.47). We provided evidence that, ER was comparable to surgery in terms of the 5-year overall survival. In addition, ER had a lower rate of complications and shorter hospital stay, but a higher rate of local recurrence and metachronous lesions for the treatment of early gastric cancer and precancerous lesions. |
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Demographic breakdown
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Student > Bachelor | 2 | 50% |
Librarian | 1 | 25% |
Unknown | 1 | 25% |
Readers by discipline | Count | As % |
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Arts and Humanities | 1 | 25% |
Environmental Science | 1 | 25% |
Medicine and Dentistry | 1 | 25% |
Unknown | 1 | 25% |