Title |
Filamentous Influenza Viruses
|
---|---|
Published in |
Current Clinical Microbiology Reports, July 2016
|
DOI | 10.1007/s40588-016-0041-7 |
Pubmed ID | |
Authors |
Matthew D. Badham, Jeremy S. Rossman |
Abstract |
Influenza A virus is a pathogen of global medical importance causing significant health and socio-economic costs every year. Influenza virus is an unusual pathogen in that it is pleomorphic, capable of forming virions ranging in shape from spherical to filamentous. Despite decades of research on the influenza virus, much remains unknown about the formation of filamentous influenza viruses and their role in the viral replication cycle. Here, we discuss what is known about influenza virus assembly and budding, focusing on the viral and host factors that are involved in the determination of viral morphology. Whilst the biological function of the filamentous morphology remains unknown, recent results suggest a role in facilitating viral spread in vivo. We discuss these results and speculate on the consequences of viral morphology during influenza virus infection of the human respiratory tract. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 94 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 24% |
Student > Bachelor | 15 | 16% |
Student > Master | 14 | 15% |
Researcher | 11 | 12% |
Student > Doctoral Student | 3 | 3% |
Other | 6 | 6% |
Unknown | 22 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 16 | 17% |
Immunology and Microbiology | 16 | 17% |
Agricultural and Biological Sciences | 12 | 13% |
Veterinary Science and Veterinary Medicine | 5 | 5% |
Chemistry | 4 | 4% |
Other | 15 | 16% |
Unknown | 26 | 28% |