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Lectin binding studies on a glycopolymer brush flow-through biosensor by localized surface plasmon resonance

Overview of attention for article published in Analytical & Bioanalytical Chemistry, June 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (58th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

twitter
5 tweeters

Citations

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6 Dimensions

Readers on

mendeley
19 Mendeley
Title
Lectin binding studies on a glycopolymer brush flow-through biosensor by localized surface plasmon resonance
Published in
Analytical & Bioanalytical Chemistry, June 2016
DOI 10.1007/s00216-016-9667-9
Pubmed ID
Authors

Ruben R. Rosencrantz, Vu Hoa Nguyen, Hyunji Park, Christine Schulte, Alexander Böker, Uwe Schnakenberg, Lothar Elling

Abstract

A localized surface plasmon resonance biosensor in a flow-through configuration was applied for investigating kinetics of lectin binding to surface-grafted glycopolymer brushes. Polycarbonate filter membranes with pore sizes of 400 nm were coated with a 114-nm thick gold layer and used as substrate for surface-initiated atom-transfer radical polymerization of a glycomonomer. These grafted from glycopolymer brushes were further modified with two subsequent enzymatic reactions on the surface to yield an immobilized trisaccharide presenting brush. Specific binding of lectins including Clostridium difficile toxin A receptor domain to the glycopolymer brush surface could be investigated in a microfluidic setup with flow-through of the analytes and transmission surface plasmon resonance spectroscopy. Graphical abstract Glycopolymer brushes serve as high affinity ligands for lectin and toxin interactions in a sensitive, disposable flow-through LSPR biosensor.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 32%
Professor 3 16%
Student > Master 3 16%
Researcher 2 11%
Unspecified 2 11%
Other 3 16%
Readers by discipline Count As %
Chemistry 5 26%
Biochemistry, Genetics and Molecular Biology 4 21%
Materials Science 3 16%
Unspecified 2 11%
Physics and Astronomy 2 11%
Other 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2016.
All research outputs
#6,556,980
of 12,230,555 outputs
Outputs from Analytical & Bioanalytical Chemistry
#1,946
of 4,657 outputs
Outputs of similar age
#111,701
of 276,175 outputs
Outputs of similar age from Analytical & Bioanalytical Chemistry
#26
of 181 outputs
Altmetric has tracked 12,230,555 research outputs across all sources so far. This one is in the 46th percentile – i.e., 46% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,657 research outputs from this source. They receive a mean Attention Score of 2.4. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,175 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 181 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.