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The Antioxidant Effect of Exercise: A Systematic Review and Meta-Analysis

Overview of attention for article published in Sports Medicine, June 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
100 tweeters
facebook
9 Facebook pages

Citations

dimensions_citation
34 Dimensions

Readers on

mendeley
142 Mendeley
Title
The Antioxidant Effect of Exercise: A Systematic Review and Meta-Analysis
Published in
Sports Medicine, June 2016
DOI 10.1007/s40279-016-0566-1
Pubmed ID
Authors

Caio Victor de Sousa, Marcelo Magalhães Sales, Thiago Santos Rosa, John Eugene Lewis, Rosangela Vieira de Andrade, Herbert Gustavo Simões

Abstract

Physical activity has been associated with reduced oxidative stress (OS) in observational studies and clinical trials. The purpose of this systematic review and meta-analysis of controlled trials was to determine the effect of physical exercise on OS parameters. We conducted a systematic review of the literature up to March 2016 that included the following databases: PubMed, SCOPUS, and Web of Science. A keyword combination referring to exercise training and OS was included as part of a more thorough search process. We also manually searched the reference lists of the articles. From an initial 1573 references, we included 30 controlled trials (1346 participants) in the qualitative analysis, 19 of which were included in the meta-analysis. All trials were conducted in humans and had at least one exercise intervention and a paired control group. Using a standardized protocol, two investigators independently abstracted data on study design, sample size, participant characteristics, intervention, follow-up duration, outcomes, and quantitative data for the meta-analysis. Thus, the investigators independently assigned quality scores with a methodological quality assessment (MQA). The agreement level between the reviewers was 85.3 %. Discrepancies were solved in a consensus meeting. The MQA showed a total score in the quality index between 40 and 90 % and a mean quality of 55 %. Further, in a random-effects model, data from each trial were pooled and weighted by the inverse of the total variance. Physical training was associated with a significant reduction in pro-oxidant parameters (standard mean difference [SMD] -1.08; 95 % confidence interval [CI] -1.57 to -0.58; p < 0.001) and an increase in antioxidant capacity (SMD 1.45; 95 % CI 0.83-2.06; p < 0.001). The pooled analysis revealed that regardless of intensity, volume, type of exercise, and studied population, the antioxidant indicators tended to increase and pro-oxidant indicators tended to decrease after training. Therefore, we conclude that exercise training seems to induce an antioxidant effect. Thus, it is suggested that people practice some kind of exercise to balance the redox state, regardless of their health status, to improve health-related outcomes.

Twitter Demographics

The data shown below were collected from the profiles of 100 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Chile 1 <1%
United States 1 <1%
Turkey 1 <1%
Unknown 138 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 22%
Student > Master 21 15%
Student > Postgraduate 16 11%
Student > Bachelor 16 11%
Unspecified 15 11%
Other 43 30%
Readers by discipline Count As %
Medicine and Dentistry 31 22%
Sports and Recreations 24 17%
Unspecified 24 17%
Nursing and Health Professions 18 13%
Agricultural and Biological Sciences 12 8%
Other 33 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 65. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2017.
All research outputs
#259,263
of 13,382,064 outputs
Outputs from Sports Medicine
#285
of 2,186 outputs
Outputs of similar age
#9,344
of 266,445 outputs
Outputs of similar age from Sports Medicine
#8
of 35 outputs
Altmetric has tracked 13,382,064 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,186 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,445 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.