Prediction of Nonlinear Intestinal Absorption of CYP3A4 and P-Glycoprotein Substrates from their In Vitro Km Values

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PK/ADME Consulting, LLC, 10 Jun 2012

Here is an approach to predict which P-gp and/or CYP 3A4 substrates may follow linear absorption kinetics.http://www.springerlink…