| Title |
Characterization of Bifidobacterium spp. strains for the treatment of enteric disorders in newborns
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, May 2012
|
| DOI | 10.1007/s00253-012-4138-5 |
| Pubmed ID | |
| Authors |
Irene Aloisio, Cecilia Santini, Bruno Biavati, Giovanni Dinelli, Avrelija Cencič, Walter Chingwaru, Luca Mogna, Diana Di Gioia |
| Abstract |
Several studies support the use of probiotics for the treatment of minor gastrointestinal problems in infants. Positive effects on newborn colics have been evidenced after administration of Lactobacillus strains, whereas no studies have been reported regarding the use of bifidobacteria for this purpose. This work was therefore aimed at the characterization of Bifidobacterium strains capable of inhibiting the growth of pathogens typical of the infant gastrointestinal tract and of coliforms isolated from colic newborns. Among the 46 Bifidobacterium strains considered, 16 showed high antimicrobial activity against potential pathogens; these strains were further characterized from a taxonomic point of view, for the presence and transferability of antibiotic resistances, for citotoxic effects and adhesion to nontumorigenic gut epithelium cell lines. Moreover, their ability to stimulate gut health by increasing the metabolic activity and the immune response of epithelial cells was also studied. The examination of all these features allowed to identify three Bifidobacterium breve strains and a Bifidobacterium longum subsp. longum strain as potential probiotics for the treatments of enteric disorders in newborns such as infantile colics. A validation clinical trial involving the selected strains is being planned. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 1% |
| France | 1 | 1% |
| Unknown | 98 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 19% |
| Student > Master | 13 | 13% |
| Student > Ph. D. Student | 12 | 12% |
| Student > Bachelor | 11 | 11% |
| Student > Doctoral Student | 7 | 7% |
| Other | 17 | 17% |
| Unknown | 21 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 38% |
| Medicine and Dentistry | 13 | 13% |
| Nursing and Health Professions | 5 | 5% |
| Immunology and Microbiology | 4 | 4% |
| Biochemistry, Genetics and Molecular Biology | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 25 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2024.
All research outputs
#4,931,650
of 24,119,703 outputs
Outputs from Applied Microbiology and Biotechnology
#1,169
of 8,034 outputs
Outputs of similar age
#32,115
of 167,387 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#12
of 74 outputs
Altmetric has tracked 24,119,703 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,034 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,387 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.