↓ Skip to main content

Low-level laser therapy in different stages of rheumatoid arthritis: a histological study

Overview of attention for article published in Lasers in Medical Science, April 2012
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
4 tweeters
facebook
6 Facebook pages
video
1 video uploader

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
38 Mendeley
Title
Low-level laser therapy in different stages of rheumatoid arthritis: a histological study
Published in
Lasers in Medical Science, April 2012
DOI 10.1007/s10103-012-1102-7
Pubmed ID
Authors

Ana Carolina Araruna Alves, Paulo de Tarso Camillo de Carvalho, Marcio Parente, Murilo Xavier, Lucio Frigo, Flávio Aimbire, Ernesto Cesar Pinto Leal Junior, Regiane Albertini

Abstract

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of unknown etiology. Treatment of RA is very complex, and in the past years, some studies have investigated the use of low-level laser therapy (LLLT) in treatment of RA. However, it remains unknown if LLLT can modulate early and late stages of RA. With this perspective in mind, we evaluated histological aspects of LLLT effects in different RA progression stages in the knee. It was performed a collagen-induced RA model, and 20 male Wistar rats were divided into 4 experimental groups: a non-injured and non-treated control group, a RA non-treated group, a group treated with LLLT (780 nm, 22 mW, 0.10 W/cm(2), spot area of 0.214 cm(2), 7.7 J/cm(2), 75 s, 1.65 J per point, continuous mode) from 12th hour after collagen-induced RA, and a group treated with LLLT from 7th day after RA induction with same LLLT parameters. LLLT treatments were performed once per day. All animals were sacrificed at the 14th day from RA induction and articular tissue was collected in order to perform histological analyses related to inflammatory process. We observed that LLLT both at early and late RA progression stages significantly improved mononuclear inflammatory cells, exudate protein, medullary hemorrhage, hyperemia, necrosis, distribution of fibrocartilage, and chondroblasts and osteoblasts compared to RA group (p < 0.05). We can conclude that LLLT is able to modulate inflammatory response both in early as well as in late progression stages of RA.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 18%
Student > Bachelor 7 18%
Student > Master 5 13%
Unspecified 4 11%
Student > Doctoral Student 4 11%
Other 11 29%
Readers by discipline Count As %
Medicine and Dentistry 15 39%
Unspecified 7 18%
Nursing and Health Professions 5 13%
Agricultural and Biological Sciences 4 11%
Neuroscience 3 8%
Other 4 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2019.
All research outputs
#3,096,712
of 13,511,623 outputs
Outputs from Lasers in Medical Science
#95
of 909 outputs
Outputs of similar age
#24,893
of 121,720 outputs
Outputs of similar age from Lasers in Medical Science
#2
of 6 outputs
Altmetric has tracked 13,511,623 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 909 research outputs from this source. They receive a mean Attention Score of 2.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,720 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.