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Biological effects of inhaled nitrogen dioxide in healthy human subjects

Overview of attention for article published in International Archives of Occupational and Environmental Health, May 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#12 of 2,128)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
6 news outlets
blogs
1 blog
twitter
75 X users
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
36 Mendeley
Title
Biological effects of inhaled nitrogen dioxide in healthy human subjects
Published in
International Archives of Occupational and Environmental Health, May 2016
DOI 10.1007/s00420-016-1139-1
Pubmed ID
Authors

P. Brand, J. Bertram, A. Chaker, R. A. Jörres, A. Kronseder, T. Kraus, M. Gube

Abstract

Several epidemiological studies indicate that inhaled nitrogen dioxide (NO2) at low concentrations have been statistically associated with adverse health effects. However, these results are not reflected by exposure studies in humans. The aim of the study was to assess the acute functional and cellular responses to different NO2 concentrations in healthy human subjects with various techniques. Twenty-five subjects were exposed for 3 h to NO2 concentrations 0, 0.1, 0.5, and 1.5 ppm in a randomized crossover study design during 4 consecutive weeks. In each subject, lung function, diffusion capacity and exhaled nitric oxide were measured and inflammation markers were assessed in blood, nasal secretions, induced sputum and exhaled breath condensate. From all lung function indices under consideration, only intrathoracic gas volume was borderline significantly increased after 0.5 ppm (p = 0.048) compared to 0.1 ppm NO2. Regarding the cellular effect parameters, the macrophage concentration in induced sputum decreased with increasing NO2 concentration, although these changes were only borderline significant (p = 0.05). These results do not suggest a considerable acute adverse response in human subjects after 3 h of exposure to NO2 in the NO2 concentration range investigated in this study.

X Demographics

X Demographics

The data shown below were collected from the profiles of 75 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 19%
Researcher 6 17%
Other 5 14%
Student > Doctoral Student 2 6%
Student > Bachelor 2 6%
Other 5 14%
Unknown 9 25%
Readers by discipline Count As %
Medicine and Dentistry 6 17%
Environmental Science 4 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 11%
Engineering 3 8%
Agricultural and Biological Sciences 2 6%
Other 6 17%
Unknown 11 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 114. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2023.
All research outputs
#370,847
of 25,501,527 outputs
Outputs from International Archives of Occupational and Environmental Health
#12
of 2,128 outputs
Outputs of similar age
#6,729
of 312,770 outputs
Outputs of similar age from International Archives of Occupational and Environmental Health
#2
of 9 outputs
Altmetric has tracked 25,501,527 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,128 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,770 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.